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Studies in Cellular Growth

I. Effect of Antisplenic-Tissue-Serum on Experimentally Induced Wounds in Mice

From the Tobey Maltz Foundation^,4

Abstract

1. A 0.1 unit/kg dose of antisplenic-tissue-serum (ASTS) accelerates the healing process of experimental wounds in mice.

2. Pretreatment with one dose of ASTS (0.1 unit/kg) did not affect the normal course of healing.

3. A 10 unit/kg dose of antisplenic-tissue-serum (ASTS) did not affect the rate of healing as compared with control treated groups.

4. The presence of anti-mouse red blood cell factors in the antiserum did not modify the action of the ASTS.

Footnotes

¹ Tobey Maltz Foundation.

² Dept. of Pathology, Bellevue Hospital, N. Y. C.

³ Biological Laboratories, Inc., 16 Clinton St., Brooklyn, N. Y.

⁴ Performed under the auspices of the Tobey Maltz Foundation, Inc., 57 W. 57, N. Y. C.