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The Journal of Immunology, 1921, 6: 445-451.
Copyright © 1921 by The American Association of Immunologists, Inc.

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The Influence of Temperature Upon the Agglutination of the Red Blood Corpuscles

Fredrik Jervell

From Rikshospitalet, Kristiania, Norway

Abstract

The experiments show a marked difference in the agglutination of red corpuscles at low and at high temperatures.

The most pronounced agglutination is obtained in the ice chest. It is shown that this is due to a quicker or more nearly complete adsorption of agglutinin at low than at high temperature.

After adsorption at 8° the corpuscles again lose part of the agglutinin when brought into higher temperatures.

The experiments seem to indicate that the maximal adsorption of agglutinin is different at different temperatures and more nearly complete at the low than at the high temperatures. When, therefore, the adsorption has been carried out at a low temperature and the corpuscles after that are placed at a higher temperature, they can retain only the quantity of agglutinin that corresponds to the maximum for the respective temperature and accordingly lose agglutinin until this maximum is reached.







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