HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Maltaner, F. Articles by Johnston, E. Search for Related Content PubMed Articles by Maltaner, F. Articles by Johnston, E.

Observations upon the Conglutination Phenomenon¹

From the Division of Laboratories and Research, New York State Department of Health, Albany

Abstract

1. The conglutination phenomenon described by Bordet was reproduced using a mixture of inactivated bovine serum and fresh horse serum with washed guinea-pig cells.

2. When the bovine and horse sera used were first depleted of their fibrinogen by secondary coagulation induced by treatment of the active sera with blood platelets, they no longer gave rise to this "conglutination" phenomenon.

3. Not only the conglutination of guinea-pig blood cells, but also the hemolysis and agglutination of these cells by both sera when used separately or in mixtures, depended upon the presence of fibrinogen and a heat-sensitive serum constituent.

4. The degree of agglutination or hemolysis obtained in the presence of the heat-sensitive serum constituents depends, in part at least, upon the quantity of fibrinogen present.

Footnotes

¹ Reported at the Eighth Annual Meeting of The American Association of Immunologists, Cleveland, Ohio, March 24–25, 1921.