HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Harris, T. N. Articles by Stokes, J. Search for Related Content PubMed Articles by Harris, T. N. Articles by Stokes, J., Jr.

A Study of the Role of the Thymus and Spleen in the Formation of Antibodies in the Rabbit

From The Children's Hospital of Philadelphia, and the Harrison Department of Surgical Research, School of Medicine, University of Pennsylvania

Abstract

1. The thymus did not play a demonstrable role in the formation of antibodies by the young rabbit, or in the retention of antibodies derived by the fetus from the maternal circulation.

2. Only slight evidence of formation of antibodies in the spleen was shown following the subcutaneous injection of antigens. Following intravenous injection of antigens, however, high antibody-titers were demonstrated in splenic extracts.

3. The failure of the thymus to form antibodies, which is in contrast with ecent and current observations on the lymph-nodes and spleen is discussed in erms of the architectural differences between the thymus and those organs.

This article has been cited by other articles:

				A. P. Monaco, M. L. Wood, and P. S. Russell Adult Thymectomy: Effect on Recovery from Immunologic Depression in Mice Science, July 23, 1965; 149(3682): 432 - 435. [Abstract] [PDF]