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Production of Types a, b, c, d, e and f H. Influenzae Antibody for Diagnostic and Therapeutic Purposes¹

Abstract

The procedures used for type b H. influenzae antibody-production are satisfactory for making type-specific antibody for the other five types. The determination of agglutinin-nitrogen for measuring type b antibody-content appears to be applicable to the other five types of H. influenzae antisera. Additional study is required to determine whether the variation in total antibody produced against the different types in comparable numbers of rabbits is due to the particular strain of types used or is related to inherent characteristics of the types.

Footnotes

¹ These investigations were aided through the Commission on Influenza, Board for the Investigation and Control of Influenza and other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army, and also in part by The Commonwealth Fund.