HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Rice, C. E. Search for Related Content PubMed Articles by Rice, C. E.

Studies of the Complement-Fixation Reaction in Virus Systems

I. Activities of Vaccinia Virus Antigens and Antisera¹

From the Division of Laboratories and Research, New York State Department of Health, Albany

Abstract

From these studies of vaccinial systems a short quantitative method of titrating the complement-fixing capacity of vaccinial sera and antigens has been derived. The method is based on that developed in this laboratory (5) for the routine complement-fixation test for syphilis, and involves the use of tables of conversion factors for the determination of the amount of complement needed for 50-per-cent hemolysis under various conditions. The test has been useful in differentiating reactions of sera with several different antigens and of antigens with different sera.

Footnotes

¹ The author is very grateful to Dr. W. R. Thompson for advice in regard to the mathematical discussion in the paper.