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The Journal of Immunology, 1945, 51: 173-189.
Copyright © 1945 by The American Association of Immunologists, Inc.

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Experimental Studies on the Yellow Fever Protection Test

K. C. Smithburn1

From the Yellow Fever Research Institute, Entebbe, Uganda,2

Abstract

A considerable amount of experimental work has been done on the yellow fever protection test, as result of which we have adopted for use in Uganda an intraperitoneal technic which employs 1 per cent mouse passage virus. The method enables tests to be done with as little as 0.5 ml of serum. It is more sensitive for the detection of antibody in low titer than the standard intraperitoneal method and appears to be no less specific than the latter.

Footnotes

1 Staff Member of the International Health Division, Rockefeller Foundation.

2 This Institute is supported jointly by the Medical Department of the Uganda Protectorate and the International Health Division of The Rockefeller Foundation.







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