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The Journal of Immunology, 1920, 5: 521-527.
Copyright © 1920 by The American Association of Immunologists, Inc.

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The Sachs-Georgi Precipitation Test for Syphilis

Thomas G. Hull and Eva E. Faught

From the Illinois Department of Public Health

Abstract

1. A modification of the Sachs-Georgi precipitation test for syphilis is described, using clear blood serum and an alcoholic extract of beef heart, either cholesterinized or not.
2. The precipitation test agreed with the Wassermann test in 88 per cent of the cases; in 7 per cent it was more delicate, giving positive results where the Wassermann was negative; in 3 per cent it was negative where the Wassermann was doubtful; in 2 per cent it was negative where the Wassermann was positive. Treatment of the patient apparently affects the results of the precipitation causing it at times to come negative while the Wassermann still is positive.
3. Attempts to determine whether the precipitate formed in this test was entirely responsible for the Wassermann reaction were unsuccessful.




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