HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Schmidt, C. L. A. Search for Related Content PubMed Articles by Schmidt, C. L. A.

The Antigenic Properties of Hemocyanin¹

From the Department of Biochemistry and Pharmacology of the University of California

Abstract

1. Hemocyanin prepared from the circulating fluid of the abalone (Haliotis) was precipitated by ammonium sulphate within the limits found by Alsberg and Clark from Limulus polyphemus. It appears to be a globulin.

2. The sera of rabbits immunized with this preparation of hemocyanin gave positive fixation and precipitin tests. It was toxic for guinea-pigs previously sensitized to this substance but not toxic for normal animals.

3. These experiments support the chemical viewpoint that the chemical makeup of hemocyanin is very different from hemoglobin since the latter is non-antigenic.

Footnotes

¹ Aided by a grant from the George Williams Hooper Foundation for Medical Research.