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Additional Variants of the Rh Type Demonstrable with a Special Human Anti-Rh Serum¹

From the Bacteriological and Serological Laboratory of the Office of the Chief Medical Examiner of New York City

Abstract

A serum is described from the mother of an erythoblastotic baby, which in addition to the usual anti-Rh agglutinins contains a special agglutinin of high titer which agglutinated only about of all bloods. The agglutinin in question proved to be a special type of anti-Rh agglutinin reacting with about of Rh₂ bloods and only about of Rh₁ bloods. The special agglutinogen detected by the serum is apparently inherited as a simple Mendelian dominant, presumably due to the action of a special allelic gene.

Footnotes

¹ Aided by a grant from the Carnegie Corporation and the Committee on Human Heredity of the National Research Council.

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