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The Journal of Immunology, 1943, 46: 101-111.
Copyright © 1943 by The American Association of Immunologists, Inc.

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Nonspecific Factors in Resistance

VI. Incidence of Common Cold in Persons with and Without the Accessory Symptomatology of Nonreaginic Food-Allergy

WM. B. Brown, Irma Graham, Ariel Niedringhaus and Arthur Locke

From the Division of Health Education, Stephens College, Columbia, Mo., and the Institute of Pathology, The Western Pennsylvania Hospital, Pittsburgh

Abstract

An investigation is reported which extends the evidence recently reported by Coca for the existence of a cause-and-effect relationship between presence of nonreaginic food-allergy and predisposition to common cold. Two or more of Coca's 11 symptomatic evidences of the presence of nonreaginic food-allergy were found to be present in 79 per cent of a group of 422 girls of college age. Each of the symptoms, when present, was associated on the average with a higher colds-incidence than was observed in the absence of symptoms. A progressively higher colds-incidence was found with increasing number of symptoms. No correlation was found between presence of symptomatology and percentage appearing to be in poor condition on a basis of performance during a modification of the Flack test. Handicap from poor condition, appraised as described, was, however, reflected in a heightened colds-incidence as was handicap from addiction to smoking. The girls with the greatest total handicap, from all sources, had roughly 4 times as many colds as those with the least.







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