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The Journal of Immunology, 1942, 45: 123-126.
Copyright © 1942 by The American Association of Immunologists, Inc.

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An Effect of Temperature Upon Antibody-Production in Fish

J. E. Cushing, Jr.

From the William G. Kerckhoff Laboratories of the Biological Sciences, California Institute of Technology

Abstract

A study was made upon the rate of production of agglutinins against sea urchin sperm in carp and gold fish held at two different temperatures (15 and 28 degrees). The fish, four of each kind at each temperature, were bled every few days from the heart and agglutinative tests made on their sera. These showed that the antibody-titer of the fish kept in the warm tank rose at least four days sooner than that of those kept in the cold tank. This indicates, in agreement with other work, that temperature does influence the rate of antibody-production in cold-blooded vertebrates.







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