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The Polyvalency of Crotalidic Antivenins

IV. Antinecrotic, Anticoagulant and Antiproteolytic Actions

Mulford Biological Laboratories, Sharp and Dohme, Glenolden, Pa.

Abstract

1. Different lots of venom of the same species agree in their proteolytic activity.

2. The venoms of different species of pit viper show great differences, which are not correlated with other actions of the venoms.

3. Antivenins are irregular and uncertain in their neutralizing action and show no evidence of specificity.