HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ferguson, L. C. Search for Related Content PubMed Articles by Ferguson, L. C.

Heritable Antigens in the Erythrocytes of Cattle^1,2,

From the University of Wisconsin

Abstract

Nine antigens were identified in the erythrocytes of cattle by means of immune isolysins. A single antibody for each of three antigens, A, B, and C, was found in as many different immune sera. Each of two other sera contained antibodies for three substances, one of them for antigens D, E, and F, and the other for antigens G, H, and I. Reagents were prepared from the antisera with which the cells of other cattle were tested for the presence of these different characters. Two of these antigens, B and D, are probably the same substance and likewise C and F are presumably identical.

A study of seven of the antigens in 104 offspring suggested that each was inherited as if controlled by a single gene. Antigens C (or F) and E are closely related and presumably are controlled by allelomorphic genes. The other five characters, A, B (or D), G, H, and I appear to be independent of the former system and also of each other.

The cells of an individual contained a particular antigen only if one or both parents possessed it. This type of inheritance allows for the use of this technic in excluding certain animals as the parents of a calf whose identification is questioned.

Footnotes

¹ From the Departments of Veterinary Science and Genetics (paper No. 266), in cooperation with the Bureau of Animal Industry, United States Department of Agriculture. Published with the approval of the Director of the Experiment Station. This investigation was supported in part by the American Guernsey Cattle Club and the Holstein-Friesian Association of America. Assistance in certain parts of the work was furnished by the personnel of Works Projects Administration, Official Project No. 65-1-53-2349.

² Submitted in partial fulfillment of the requirements for the Degree of Doctor of Philosophy to the faculty of the Graduate School, University of Wisconsin.

This article has been cited by other articles:

				R. D. OWEN IMMUNOGENETIC CONSEQUENCES OF VASCULAR ANASTOMOSES BETWEEN BOVINE TWINS Science, October 19, 1945; 102(2651): 400 - 401. [PDF]