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On Red Cell Globulin¹

From the Department of Biochemistry and Pharmacology, University of California

Abstract

1. It was found that the sera of animals immunized with CO₂-globulin from washed red cells contained immune bodies specific for this globulin and not for the CO₂-globulin from the homologous serum and substances which in the presence of alexin will cause lysis of the homologous red cells and in the absence of alexin, agglutination of these cells.

2. It cannot be definitely stated whether the CO₂-globulin from red cells is the antigen concerned in the production of a lysin for the homologous red cell or a substance intimately associated with it. The possibilities are discussed.

Footnotes

¹ Aided in part by a grant from the George Williams Hooper Foundation for Medical Research.