HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Dragstedt, C. A. Articles by Youmans, G. P. Search for Related Content PubMed Articles by Dragstedt, C. A. Articles by Youmans, G. P.

Passive Sensitization of Rabbit's Blood

From the Department of Physiology and Pharmacology and the Department of Bacteriology, Northwestern University Medical School, Chicago

Abstract

In early studies upon anaphylaxis in rabbits it was reported by Friedemann (1) and by Scott (2) that no latent period was necessary for the passive sensitization of these animals to the subsequent intravenous injection of antigen such as has been shown to be necessary for the guinea-pig and dog. These observations have been rather generally discounted or explained as being anaphylactoid reactions not truly anaphylactic in character. Such an explanation fails to explain why the simultaneous injection of antigen and antiserum does not provoke reactions in either guinea-pigs or dogs with equal facility to that in rabbits and has no bearing at all upon the observations of Opie (3) and others that the Arthus phenomenon can be produced in rabbits by the subcutaneous injection of antigen either before, simultaneously or after the injection of antiserum.