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The Journal of Immunology, 1940, 39: 457-460.
Copyright © 1940 by The American Association of Immunologists, Inc.
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The Failure of Histaminase to Protect Guinea-Pigs Against Histamine and Anaphlyactic Shock

H. L. Alexander and Donald Bottom

From the Department of Internal Medicine, Washington University and Barnes Hospital, St. Louis, Missouri

Abstract

1. Pretreatment with histaminase fifteen minutes before injection of guinea pigs with histamine failed to protect them against fatal shock.
2. Similarly, histaminase so given did not protect against anaphylactic shock.






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