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The Journal of Immunology, 1940, 39: 383-396.
Copyright © 1940 by The American Association of Immunologists, Inc.

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The Rôle of Diffusion in the Pneumococcus-Antipneumococcus Reaction

A. D. Hershey

Department of Bacteriology and Immunology, Washington University School of Medicine, St. Louis, Missouri)

Abstract

The absolute rate of the pneumococcus-antipneumococcus reaction predicted by diffusion-theory has been found to agree with the results of protection-experiments. Apparently each molecule of antibody impinging upon the free cell-surface is irreversibly bound. The indifference of the reaction to temperature provides independent confirmation of this conclusion concerning the mechanism of the reaction.




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G. M. KALMANSON and J. BRONFENBRENNER
THE REVERSAL OF PNEUMOCOCCUS QUELLUNG BY DIGESTION OF THE ANTIBODY WITH PAPAIN
Science, July 3, 1942; 96(2479): 21 - 22.
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