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Contact-Reactions in Atopy¹

I. Contact-Reactions to Silkworm in Atopic Subjects

From the Division of Allergy of the Jewish Hospital of Brooklyn, New York

Abstract

1. A special type of contact-reaction to an oil-free preparation of silkworm has been described.

2. This form of hypersensitiveness seems to occur most frequently in atopic children.

3. It is not based upon the presence of atopic reagin and cannot be passively transferred to normal skin.

4. The reaction is specific and may at times be induced by single or repeated applications of silkworm to the skin.

5. The excitant is not the oil but is probably a protein.

6. Dialyzed extracts of silkworm were found to contain the active excitant and produced positive contact-reactions.

Footnotes

¹ Read at the Semi-Annual Meeting of the Division of Allergy, Jewish Hospital of Brooklyn, November 21, 1938.