HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Rake, G. Articles by Shaffer, M. F. Search for Related Content PubMed Articles by Rake, G. Articles by Shaffer, M. F.

Studies on Measles

I. The Use of the Chorio-Allantois of the Developing Chicken Embryo

From the Division of Microbiology, the Squibb Institute for Medical Research, New Brunswick, N. J.

Abstract

1. The agent of measles, obtained from the blood or pharyngeal washings of human cases, has been propagated by serial passage on the chorio-allantois of the fertile hen's egg in the absence of regularly occurring, transmissible, macroscopic lesions.

2. The presence of the agent has been demonstrated by the inoculation of pooled chorio-allantois and viscera of the chick embryos into monkeys (Macacus mulatta) with the production of a disease indistinguishable from that brought about by the injection of material obtained from cases of human measles.

3. From monkeys infected with material from either source, measles virus can be isolated from the blood and nasal washings during the period of acute disease and again propagated in the fertile hen's egg.

4. Certain properties of the virus have been elucidated during the course of the work.