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A Simplified Formula for Diphtheric Toxin Broth

From the Department of Bacteriology and Immunology, Harvard University Medical School¹

Abstract

Detailed directions are given for the preparation of a peptone— and meat infusion—free medium upon which a relatively powerful (60 Lf.) diphtheric toxin may be regularly obtained with a strain of the Park 8 organism. The problem of still further improvements in this medium is under investigation in this laboratory, as is the question of toxin production by other strains of C. diphtheriae.

Footnotes

¹ The writer wishes to acknowledge with thanks the courtesies of various members of the Faculty of Medicine, Dalhousie University, Halifax, in whose laboratories a part of this work was carried out during the summer of 1938.