HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mengle, H. A. Articles by Bower, J. O. Search for Related Content PubMed Articles by Mengle, H. A. Articles by Bower, J. O.

A Supplementary Report on the Importance of Clostridium Welchii as an Etiologic Factor in the Toxemia of Spreading Peritonitis Following Acute Perforative Appendicitis

From the Department of Research Surgery, Temple University School of Medicine, and the Mulford Biological Laboratories of Sharp and Dohme, at Glenolden, Pa.

Abstract

Of the 20 dogs which were immunized and operated on as described, 13 lived and 7 died, a mortality of 35 per cent. This mortality may be compared with a control mortality previously established in earlier investigations, of over 91 per cent. The complete details are shown in table 2. While our series of animals is not so large as could be desired, yet the marked drop in mortality in this group as compared with the control group leads one to believe that the toxemia accompanying spreading peritonitis may be largely produced by the toxin of Clostridium welchii.