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Studies on Serum Fractions

III. Precipitation of Antibody by Precipitin-Serum

Hygienic Institute (Eisei-kenkyusho) of the S. M. R. Co., Dairen, Manchuria

Abstract

Diphtheric antitoxin is precipitable by the precipitating serum prepared with the floccules of diphtheric toxoid-antitoxin (P.V.At.), whereas pneumococcal antibody is precipitated by the precipitating serum prepared with specific precipitates of pneumococcal SSS (P.V.Ab.) in their optimal proportions and also in the range of excessive precipitin. The former precipitating serum absorbs also antipneumococcal antibody from antipneumococcal horse serum, but it is only in the range of the mixtures containing far less antipneumococcal serum than the quantity present in the optimal proportion. The latter precipitating serum absorbs also antitoxin from antidiphtheric horse serum, but this absorption occurs only in the secondary zone and not in the primary or main zone.