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Studies on the Mechanism of Immunity in Typhus Fever¹

Complement-Fixation in Typhus Fever

From the Department of Bacteriology and Immunology, Harvard University Medical School, Boston, Massachusetts

Abstract

Typhus-immune serum contains complement-binding antibodies for Rickettsia prowazeki (Mexican type), but not for B. proteus X-19 or X-19 SSS.

The sera from rabbits immunized against B. proteus X-19 fix complement in the presence of Rickettsia prowazeki as well as with the homologous antigens.

Footnotes

¹ This work was partially supported by a grant from the DeLamar Mobile Research Fund.

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