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A Procedure for the Serological Determination of Blood-Relationship of Ancient and Modern Peoples with Special Reference to the American Indians

I. A Procedure for the Determination of Isoantigens in Saliva

From the Department of Bacteriology and Immunology, Washington University Medical School, St. Louis, Missouri

E. O. Brady

Washington University Dental School,St. Louis, Missouri

Abstract

1. An examination of saliva from individuals of the various blood-groups served to emphasize the fact observed by others that the antigens are not demonstrable in the saliva of all persons.

2. It was found that group-antigens in saliva are present in the secretion itself and their occurrence there is not determined by the presence of epithelial cells or blood.

3. The experiments indicate clearly that although the group-ferments in saliva may under suitable conditions destroy the antigens, they are not the only factors determining the absence of A or B substance in saliva.

4. In a study of families it was found that the presence or absence of group-antigen in saliva presented no exception to the Mendelian laws of inheritance.

Footnotes

¹ Present address, Biology Department, University of Montana, Missoula, Montana.