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The Journal of Immunology, 1936, 30: 291-300.
Copyright © 1936 by The American Association of Immunologists, Inc.
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Antigenic Properties of Brain Tumors1

Arthur Weil and Erich Liebert

From the Institute of neurology, Northwestern University Medical School

Abstract

Following intraperitoneal injections into guinea pigs and intravenous injections into white rabbits, saline emulsions of gliomas and brain tissue in combination with dog serum as a carrier stimulated the production of specific antibodies. A higher titer of the antiserum was obtained following intravenous injections into white rabbits of alcoholic extracts of formalin fixed brains and gliomas. Alcoholic extracts of meningiomas did not stimulate the production of specific antibodies.

The serum of a patient with glioblastoma multiforme contained antibodies against glioblastoma together with antibodies against human brain.

Footnotes

1 Read at the meeting of the Association for Research in Nervous and Mental Disease, December 27, 1935.






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