HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Jacobs, J. Search for Related Content PubMed Articles by Jacobs, J.

Serological Studies on Iodinated Sera¹

I. Precipitins and Precipitinogens

From the Laboratories of Bacteriology and Immunology Harvard Medical School

Abstract

1. When iodine is added to animal sera without the presence of acid or alkali, substances are formed which precipitate with antisera prepared from iodinated sera.

2. This change takes place in the presence of aqueous solutions as dilute as N/32.

3. Wormall's observation that diiodotyrosine, but not potassium iodide, inhibits precipitation specifically in systems of iodinated proteins and their antisera, was confirmed.

4. The specificity of substances formed in sera iodinated in neutral solutions was tested in several ways. Their specificity is similar to that of other iodinated proteins.

Footnotes

¹ The author wishes to thank Dr. Hans Zinsser, in whose laboratory this work was carried out, for his kind interest and numerous suggestions.