HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Richardson, L. V. Search for Related Content PubMed Articles by Richardson, L. V.

Diphtheria Antibodies Transmitted to the Offspring of Immune Guinea Pigs

From the Department of Bacteriology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee

Abstract

Measurements were made of the diphtheria antibodies, antibacterial and antitoxic, in the sera of the offspring of guinea pigs previously immunized with diphtheria filtrate. The data showed that diphtheria antibodies of the antibacterial sort as well as antitoxin are placentally transmittted. The proportion of
found in the sera of the offspring shortly after birth was comparable to that in the sera of their respective mothers.

The sera of a number of families were studied over periods of sixty or more days following the births; the data of these tests showed that the amount of antibodies originally transferred by the mother is the important factor in determining the duration of the passive immunity of the offspring.

Footnotes

¹ Submitted to the Graduate School of Vanderbilt University in partial fulfillment of the requirements for the degree of Doctor of Philosophy.