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A Study of Action of Saliva and Extract of Tonsils Upon Diphtheria Bacillus and Diphtheria Toxin^1,2,

From the Department of Bacteriology, School of Medicine and Dentistry, University of Rochester, Rochester, New York

Abstract

This preliminary report records the results of experimental tests of the action of saliva and extracts of tonsils and other organs upon diphtheria bacilli and diphtheria toxin. Evidence is presented which seems to indicate that some specimens of saliva may exert an anti-bacterial action against diphtheria bacilli and that saline extracts of tonsils and lymph nodes may inhibit the necrotizing action of diphtheria toxin. Whether or not these reactions are specific, has not been determined and the experiments do not permit the drawing of definite conclusions at this time.

Footnotes

¹ Presented at the annual meeting of the American Association of Immunologists, April 1, 1931, at Cleveland, Ohio.

² Part of the expenses of this investigation were defrayed by the Hungarian Fellowship section of the Rockefeller Foundation.