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Studies in the Transmission of Sensitization Fromm Other to Child in Human Beings

I. Transfer of Skin Sensitizing Antibodies

From the Department of Pediatrics, New York University, and the Children's Medical Service of Bellevue Hospital, with the coöperation of the Lying-In Hospital, New York

Abstract

Five cases of asthma and five of hay fever in pregnant women were studied by the Prausnitz-Küstner method as to the passage of antibodies through the placenta from mother to child. In each case the ability of the mother's serum, while she was carrying the child, to give a local passive transfer to a normal individual was established, in most cases with the serum diluted 1:40 and in 1 case as high as 1:320. In no case could similarproperties be shown in the undiluted cord blood or the undiluted child's blood.

Footnotes

¹ Read at a meeting of the Second International Congress of Pediatrics at Stockholm, August 21, 1930.

² Read at a meeting of The Society for the Study of Asthma and Allied Conditions at Atlantic City, May 2, 1931.