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The Journal of Immunology, 1930, 19: 417-428.
Copyright © 1930 by The American Association of Immunologists, Inc.

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The Bactericidins of B. Typhosus and B. Enteritidis Antisera

William M. Hale

From the Department of Immunology, Yale University School of Medicine, New Haven, Connecticut

Abstract

With the adoption of the receptor-analysis technic as a significant serological procedure many studies have been made which serve to introduce new interpretations into the questions of the essential relationships of the various antibodies and their contribution to the mechanisms of resistance. Even a superficial survey of the conclusions offered suggests that possibly some of the rather broad generalizations made are inadequately supported by experimental data. That two serological phenomena possess a common attribute, or are to be observed coincidently, does not of necessity prove identity, and since many of the deductions made are based upon such an assumed identity, it may well be that the reactions in question are less obviously involved in immune states than has been supposed.

The experiments here reported represent, in part, an attempt to gain further insight into such antibody-immunity relationships, and the specific point of attack bears on the question of the identity of the bactericidal amboceptors of B. enteritidis and B typhosus antisera.







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