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The Journal of Immunology, 1930, 19: 347-356.
Copyright © 1930 by The American Association of Immunologists, Inc.

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Molecular Movement, Viscosity and Agglutination

Stephen Went

From the Institute of Bacteriology and General Pathology of the University of Budapest

Abstract

1. The viscosity of the dispersing medium affects the Brownian movement of bacteria a great deal. Above a certain degree of internal friction, molecular movement ceases. The intensity of this movement depends also upon the absolute temperature.
2. Bacteria may flocculate spontaneously if the viscosity of the medium is increased to a certain degree. In this relation different microörganisms show different sensitiveness, which seems to depend upon the dimension of the bacterial surface.
3. Media of higher viscosity hinder the bacterial agglutination caused by immune sera; this is an effect on the first phase of the immune agglutination; i.e., on the process of adsorption of the immune bodies.







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