HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ando, K. Articles by Kurauchi, K. Search for Related Content PubMed Articles by Ando, K. Articles by Kurauchi, K.

Studies on the "Toxins" of Streptococcus Hemolyticus

VI. Heat-Stable Scarlatinal Toxin

From the Bacteriological Department (K Ando), Hygienic Institute (Director S. Kanai), Dairen, South Manchuria

Abstract

In the previous communications we have pointed out that there are two substances in the so-called Dick toxin with which skin reactions can be elicited in human beings. The first seems to be bacterial protein, which may be considered as the so-called nucleoprotein and the second the essential scarlatinal toxin which is heat-labile and exotoxic in nature. In more recent experiments we have found a toxic component which can not be distinguished from the heat-labile scarlatinal toxin in any way tested except in its heat stability.

1. Skin reactions were carried out on 61 (60°C.), 45 (70°C.) and 50 (80°C.) individuals (7 to 11 years of age) with 1 S.T.D. of an ordinary Dick toxin both unheated and heated for 30 minutes at various temperatures described above respectively. In this way it was found that the toxin was gradually destroyed by the increasing temperature up to 80°C., at which the destruction was practically complete.