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On the Anticomplementary Action of Pancreatic Extracts

From the Department of Serology, New York Hospital, New York City and the Department of Bacteriology and Immunology, Division of Immunology, Cornell University Medical College

Abstract

1. The anticomplementary action of the pancreatic extract known as pangestin is exhibited in a narrow quantitative zone, the larger quantities causing progressively less inhibition.

2. This zone phenomenon is not present in the digestive activity of this preparation.

3. This finding shows that the inhibition of complement by pancreatic extracts is not due to digestion of a component of complement.