| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
CUTTING EDGE |
* Institut National de la Santé et de la Recherche Médicale, Unité 503, and
Service Commun de Cytométrie, Institut Fédératif de Recherche 74, and
Laboratoire de Biologie Moléculaire et Cellulaire, Ecole Normale Supérieure de Lyon, Lyon, France
The efficiency of CD8 memory response relies partially on the modification of cellular functional capacities. To identify effector functions that can be modified following priming, we have compared the chemokines produced by naive and memory CD8 T cells. Our results show that in contrast to naive cells, resting memory CD8 T cells contain high levels of RANTES mRNA. As a result, they have the capacity to rapidly secrete RANTES upon ex vivo antigenic stimulation. In contrast to that of IFN-
, RANTES secretion is mainly due to the translation of the pre-existing mRNA.
This article has been cited by other articles:
|
|
 |
|
  C. G. Mueller, C. Boix, W.-H. Kwan, C. Daussy, E. Fournier, W. H. Fridman, and T. J. Molina Critical role of monocytes to support normal B cell and diffuse large B cell lymphoma survival and proliferation J. Leukoc. Biol., September 1, 2007; 82(3): 567 - 575. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-T. Ahn, B. Huang, L. McPherson, C. Clayberger, and A. M. Krensky Dynamic Interplay of Transcriptional Machinery and Chromatin Regulates "Late" Expression of the Chemokine RANTES in T Lymphocytes Mol. Cell. Biol., January 1, 2007; 27(1): 253 - 266. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Marcais, C.-A. Coupet, T. Walzer, M. Tomkowiak, R. Ghittoni, and J. Marvel Cell-Autonomous CCL5 Transcription by Memory CD8 T Cells Is Regulated by IL-4 J. Immunol., October 1, 2006; 177(7): 4451 - 4457. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I Tikhonov, C. Deetz, R Paca, S Berg, V Lukyanenko, J. Lim, and C. Pauza Human V{gamma}2V{delta}2 T cells contain cytoplasmic RANTES Int. Immunol., August 1, 2006; 18(8): 1243 - 1251. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Ramakrishna, R. A. Atkinson, S. A. Stohlman, and C. C. Bergmann Vaccine-Induced Memory CD8+ T Cells Cannot Prevent Central Nervous System Virus Reactivation. J. Immunol., March 1, 2006; 176(5): 3062 - 3069. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. N. Meissner, S. Swain, M. Tighe, A. Harmsen, and A. Harmsen Role of Type I IFNs in Pulmonary Complications of Pneumocystis murina Infection J. Immunol., May 1, 2005; 174(9): 5462 - 5471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Ramakrishna, S. A. Stohlman, R. A. Atkinson, D. R. Hinton, and C. C. Bergmann Differential Regulation of Primary and Secondary CD8+ T Cells in the Central Nervous System J. Immunol., November 15, 2004; 173(10): 6265 - 6273. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Sun, S. F. Abdelwahab, G. K. Lewis, and A. Garzino-Demo Recall antigen activation induces prompt release of CCR5 ligands from PBMC: implication in memory responses and immunization Int. Immunol., November 1, 2004; 16(11): 1623 - 1631. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Quemeneur, L. Beloeil, M.-C. Michallet, G. Angelov, M. Tomkowiak, J.-P. Revillard, and J. Marvel Restriction of De Novo Nucleotide Biosynthesis Interferes with Clonal Expansion and Differentiation into Effector and Memory CD8 T Cells J. Immunol., October 15, 2004; 173(8): 4945 - 4952. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. K. Sojka, D. Bruniquel, R. H. Schwartz, and N. J. Singh IL-2 Secretion by CD4+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition J. Immunol., May 15, 2004; 172(10): 6136 - 6143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Beloeil, M. Tomkowiak, G. Angelov, T. Walzer, P. Dubois, and J. Marvel In Vivo Impact of CpG1826 Oligodeoxynucleotide on CD8 T Cell Primary Responses and Survival J. Immunol., September 15, 2003; 171(6): 2995 - 3002. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
