| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Millennium Pharmaceuticals, Cambridge, MA 02139
STRL33/BONZO/TYMSTR is an orphan chemokine and HIV/SIV coreceptor
receptor that is expressed on activated T lymphocytes. We describe an
expression cloning strategy whereby we isolated a novel chemokine,
which we name CXCL16. CXCL16 is an 
(CXC) chemokine but also has
characteristics of CC chemokines and a structure similar to fractalkine
(neurotactin) in having a transmembrane region and a chemokine domain
suspended by a mucin-like stalk. A recombinant version of CXCL16 fails
to mediate chemotaxis to all known chemokine receptor transfectants
tested but does mediate robust chemotaxis, high affinity binding, and
calcium mobilization to Bonzo receptor transfectants, indicating that
this is a unique receptor ligand interaction. In vitro polarized T cell
subsets including Th1, Th2, and Tr1 cells express functional Bonzo,
suggesting expression of this receptor in chronic inflammation, which
we further verified by demonstration of CXCL16-mediated migration of
tonsil-derived CD4+ T lymphocytes. CXCL16 is expressed on
the surface of APCs including subsets of CD19+ B cells and
CD14+ monocyte/macrophages, and functional CXCL16 is also
shed from macrophages. The combination of unique structural features of
both Bonzo and CXCL16 suggest that this interaction may represent a new
class of ligands for this receptor family. Additionally, this chemokine
might play a unique dual role of attracting activated lymphocyte
subsets during inflammation as well as facilitating immune responses
via cell-cell contact.
This article has been cited by other articles:
|
|
 |
|
  C. P. Dahl, C. Husberg, L. Gullestad, A. Waehre, J. K. Damas, L. E. Vinge, A. V. Finsen, T. Ueland, G. Florholmen, S. Aakhus, et al. Increased Production of CXCL16 in Experimental and Clinical Heart Failure: A Possible Role in Extracellular Matrix Remodeling Circ Heart Fail, November 1, 2009; 2(6): 624 - 632. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Cullen, E. Germanov, T. Shimaoka, and B. Johnston Enhanced Tumor Metastasis in Response to Blockade of the Chemokine Receptor CXCR6 Is Overcome by NKT Cell Activation J. Immunol., November 1, 2009; 183(9): 5807 - 5815. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. YANABA, E. MUROI, A. YOSHIZAKI, T. HARA, F. OGAWA, K. SHIMIZU, M. YOZAKI, M. HASEGAWA, M. FUJIMOTO, K. TAKEHARA, et al. Serum CXCL16 Concentrations Correlate with the Extent of Skin Sclerosis in Patients with Systemic Sclerosis J Rheumatol, September 1, 2009; 36(9): 1917 - 1923. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Barlic, W. Zhu, and P. M. Murphy Atherogenic Lipids Induce High-Density Lipoprotein Uptake and Cholesterol Efflux in Human Macrophages by Up-Regulating Transmembrane Chemokine CXCL16 without Engaging CXCL16-Dependent Cell Adhesion J. Immunol., June 15, 2009; 182(12): 7928 - 7936. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Gutwein, M. S. Abdel-Bakky, A. Schramme, K. Doberstein, N. Kampfer-Kolb, K. Amann, I. A. Hauser, N. Obermuller, C. Bartel, A.-A. H. Abdel-Aziz, et al. CXCL16 Is Expressed in Podocytes and Acts as a Scavenger Receptor for Oxidized Low-Density Lipoprotein Am. J. Pathol., June 1, 2009; 174(6): 2061 - 2072. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Wang, Y. Lu, J. Wang, A. E. Koch, J. Zhang, and R. S. Taichman CXCR6 Induces Prostate Cancer Progression by the AKT/Mammalian Target of Rapamycin Signaling Pathway Cancer Res., December 15, 2008; 68(24): 10367 - 10377. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. H. Yang, S. J. Kim, N. Kim, J. E. Oh, J. G. Lee, N. H. Chung, S. Kim, and Y. S. Kim NKT Cells Inhibit the Development of Experimental Crescentic Glomerulonephritis J. Am. Soc. Nephrol., September 1, 2008; 19(9): 1663 - 1671. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Germanov, L. Veinotte, R. Cullen, E. Chamberlain, E. C. Butcher, and B. Johnston Critical Role for the Chemokine Receptor CXCR6 in Homeostasis and Activation of CD1d-Restricted NKT Cells J. Immunol., July 1, 2008; 181(1): 81 - 91. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Smith, B. Halvorsen, K. Otterdal, T. Waehre, A. Yndestad, B. Fevang, W. J. Sandberg, U. M. Breland, S. S. Froland, E. Oie, et al. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins Cardiovasc Res, July 1, 2008; 79(1): 195 - 203. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Meijer, J. Ogink, B. Kreike, D. Nuyten, K. E. de Visser, and E. Roos The Chemokine Receptor CXCR6 and Its Ligand CXCL16 Are Expressed in Carcinomas and Inhibit Proliferation Cancer Res., June 15, 2008; 68(12): 4701 - 4708. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D H Adams, B Eksteen, and S M Curbishley Immunology of the gut and liver: a love/hate relationship Gut, June 1, 2008; 57(6): 838 - 848. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Lu, J. Wang, Y. Xu, A. E. Koch, Z. Cai, X. Chen, D. L. Galson, R. S. Taichman, and J. Zhang CXCL16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro Mol. Cancer Res., April 1, 2008; 6(4): 546 - 554. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shimaoka, K.-i. Seino, N. Kume, M. Minami, C. Nishime, M. Suematsu, T. Kita, M. Taniguchi, K. Matsushima, and S. Yonehara Critical Role for CXC Chemokine Ligand 16 (SR-PSOX) in Th1 Response Mediated by NKT Cells J. Immunol., December 15, 2007; 179(12): 8172 - 8179. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Galkina, B. L. Harry, A. Ludwig, E. A. Liehn, J. M. Sanders, A. Bruce, C. Weber, and K. Ley CXCR6 Promotes Atherosclerosis by Supporting T-Cell Homing, Interferon-{gamma} Production, and Macrophage Accumulation in the Aortic Wall Circulation, October 16, 2007; 116(16): 1801 - 1811. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. W T van Lieshout, J. Fransen, M. Flendrie, A. M M Eijsbouts, F. H J van den Hoogen, P. L C M van Riel, and T. R D J Radstake Circulating levels of the chemokine CCL18 but not CXCL16 are elevated and correlate with disease activity in rheumatoid arthritis Ann Rheum Dis, October 1, 2007; 66(10): 1334 - 1338. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Tohyama, K. Sayama, H. Komatsuzawa, Y. Hanakawa, Y. Shirakata, X. Dai, L. Yang, S. Tokumaru, H. Nagai, S. Hirakawa, et al. CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes Int. Immunol., September 1, 2007; 19(9): 1095 - 1102. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Barlic and P. M. Murphy Chemokine regulation of atherosclerosis J. Leukoc. Biol., August 1, 2007; 82(2): 226 - 236. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Hojo, K. Koizumi, K. Tsuneyama, Y. Arita, Z. Cui, K. Shinohara, T. Minami, I. Hashimoto, T. Nakayama, H. Sakurai, et al. High-Level Expression of Chemokine CXCL16 by Tumor Cells Correlates with a Good Prognosis and Increased Tumor-Infiltrating Lymphocytes in Colorectal Cancer Cancer Res., May 15, 2007; 67(10): 4725 - 4731. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. E. Garcia, L. D. Truong, P. Li, P. Zhang, R. J. Johnson, C. B. Wilson, and L. Feng Inhibition of CXCL16 Attenuates Inflammatory and Progressive Phases of Anti-Glomerular Basement Membrane Antibody-Associated Glomerulonephritis Am. J. Pathol., May 1, 2007; 170(5): 1485 - 1496. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Lehrke, S. C. Millington, M. Lefterova, R. G. Cumaranatunge, P. Szapary, R. Wilensky, D. J. Rader, M. A. Lazar, and M. P. Reilly CXCL16 Is a Marker of Inflammation, Atherosclerosis, and Acute Coronary Syndromes in Humans J. Am. Coll. Cardiol., January 30, 2007; 49(4): 442 - 449. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. L. Fahy, S. L. Townley, and S. R. McColl CXCL16 Regulates Cell-Mediated Immunity to Salmonella enterica Serovar Enteritidis via Promotion of Gamma Interferon Production Infect. Immun., December 1, 2006; 74(12): 6885 - 6894. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. M. Aslanian and I. F. Charo Targeted Disruption of the Scavenger Receptor and Chemokine CXCL16 Accelerates Atherosclerosis Circulation, August 8, 2006; 114(6): 583 - 590. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Piqueras, J. Connolly, H. Freitas, A. K. Palucka, and J. Banchereau Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors Blood, April 1, 2006; 107(7): 2613 - 2618. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hase, T. Murakami, H. Takatsu, T. Shimaoka, M. Iimura, K. Hamura, K. Kawano, S. Ohshima, R. Chihara, K. Itoh, et al. The Membrane-Bound Chemokine CXCL16 Expressed on Follicle-Associated Epithelium and M Cells Mediates Lympho-Epithelial Interaction in GALT J. Immunol., January 1, 2006; 176(1): 43 - 51. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Agostini, A. Cabrelle, F. Calabrese, M. Bortoli, E. Scquizzato, S. Carraro, M. Miorin, B. Beghe, L. Trentin, R. Zambello, et al. Role for CXCR6 and Its Ligand CXCL16 in the Pathogenesis of T-Cell Alveolitis in Sarcoidosis Am. J. Respir. Crit. Care Med., November 15, 2005; 172(10): 1290 - 1298. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Jiang, T. Shimaoka, S. Kojo, M. Harada, H. Watarai, H. Wakao, N. Ohkohchi, S. Yonehara, M. Taniguchi, and K.-i. Seino Cutting Edge: Critical Role of CXCL16/CXCR6 in NKT Cell Trafficking in Allograft Tolerance J. Immunol., August 15, 2005; 175(4): 2051 - 2055. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Quehenberger Thematic Review Series: The Immune System and Atherogenesis. Molecular mechanisms regulating monocyte recruitment in atherosclerosis J. Lipid Res., August 1, 2005; 46(8): 1582 - 1590. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Chandrasekar, S. Mummidi, A. J. Valente, D. N. Patel, S. R. Bailey, G. L. Freeman, M. Hatano, T. Tokuhisa, and L. E. Jensen The Pro-atherogenic Cytokine Interleukin-18 Induces CXCL16 Expression in Rat Aortic Smooth Muscle Cells via MyD88, Interleukin-1 Receptor-associated Kinase, Tumor Necrosis Factor Receptor-associated Factor 6, c-Src, Phosphatidylinositol 3-Kinase, Akt, c-Jun N-terminal Kinase, and Activator Protein-1 Signaling J. Biol. Chem., July 15, 2005; 280(28): 26263 - 26277. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Xu, W. Xu, Y. Chu, Y. Gong, Z. Jiang, and S. Xiong Involvement of Up-Regulated CXC Chemokine Ligand 16/Scavenger Receptor That Binds Phosphatidylserine and Oxidized Lipoprotein in Endotoxin-Induced Lethal Liver Injury via Regulation of T-Cell Recruitment and Adhesion Infect. Immun., July 1, 2005; 73(7): 4007 - 4016. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Wysocki, A. Panoskaltsis-Mortari, B. R. Blazar, and J. S. Serody Leukocyte migration and graft-versus-host disease Blood, June 1, 2005; 105(11): 4191 - 4199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Tabata, N. Kadowaki, T. Kitawaki, T. Shimaoka, S. Yonehara, O. Yoshie, and T. Uchiyama Distribution and kinetics of SR-PSOX/CXCL16 and CXCR6 expression on human dendritic cell subsets and CD4+ T cells J. Leukoc. Biol., May 1, 2005; 77(5): 777 - 786. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G Aust, M Kamprad, P Lamesch, and E Schmucking CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves' disease (GD) Eur. J. Endocrinol., April 1, 2005; 152(4): 635 - 643. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Heydtmann, P. F. Lalor, J. A. Eksteen, S. G. Hubscher, M. Briskin, and D. H. Adams CXC Chemokine Ligand 16 Promotes Integrin-Mediated Adhesion of Liver-Infiltrating Lymphocytes to Cholangiocytes and Hepatocytes within the Inflamed Human Liver J. Immunol., January 15, 2005; 174(2): 1055 - 1062. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sato, H. Thorlacius, B. Johnston, T. L. Staton, W. Xiang, D. R. Littman, and E. C. Butcher Role for CXCR6 in Recruitment of Activated CD8+ Lymphocytes to Inflamed Liver J. Immunol., January 1, 2005; 174(1): 277 - 283. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. F. Charo and M. B. Taubman Chemokines in the Pathogenesis of Vascular Disease Circ. Res., October 29, 2004; 95(9): 858 - 866. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Fukumoto, T. Shimaoka, H. Fujimura, S. Sakoda, M. Tanaka, T. Kita, and S. Yonehara Critical Roles of CXC Chemokine Ligand 16/Scavenger Receptor that Binds Phosphatidylserine and Oxidized Lipoprotein in the Pathogenesis of Both Acute and Adoptive Transfer Experimental Autoimmune Encephalomyelitis J. Immunol., August 1, 2004; 173(3): 1620 - 1627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shimaoka, T. Nakayama, K. Hieshima, N. Kume, N. Fukumoto, M. Minami, K. Hayashida, T. Kita, O. Yoshie, and S. Yonehara Chemokines Generally Exhibit Scavenger Receptor Activity through Their Receptor-binding Domain J. Biol. Chem., June 25, 2004; 279(26): 26807 - 26810. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Abel, C. Hundhausen, R. Mentlein, A. Schulte, T. A. Berkhout, N. Broadway, D. Hartmann, R. Sedlacek, S. Dietrich, B. Muetze, et al. The Transmembrane CXC-Chemokine Ligand 16 Is Induced by IFN-{gamma} and TNF-{alpha} and Shed by the Activity of the Disintegrin-Like Metalloproteinase ADAM10 J. Immunol., May 15, 2004; 172(10): 6362 - 6372. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. M. Wuttge, X. Zhou, Y. Sheikine, D. Wagsater, V. Stemme, U. Hedin, S. Stemme, G. K. Hansson, and A. Sirsjo CXCL16/SR-PSOX Is an Interferon-{gamma}-Regulated Chemokine and Scavenger Receptor Expressed in Atherosclerotic Lesions Arterioscler Thromb Vasc Biol, April 1, 2004; 24(4): 750 - 755. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. J. Gough, K. J. Garton, P. T. Wille, M. Rychlewski, P. J. Dempsey, and E. W. Raines A Disintegrin and Metalloproteinase 10-Mediated Cleavage and Shedding Regulates the Cell Surface Expression of CXC Chemokine Ligand 16 J. Immunol., March 15, 2004; 172(6): 3678 - 3685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Hanamoto, T. Nakayama, H. Miyazato, S. Takegawa, K. Hieshima, Y. Tatsumi, A. Kanamaru, and O. Yoshie Expression of CCL28 by Reed-Sternberg Cells Defines a Major Subtype of Classical Hodgkin's Disease with Frequent Infiltration of Eosinophils and/or Plasma Cells Am. J. Pathol., March 1, 2004; 164(3): 997 - 1006. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shimaoka, T. Nakayama, N. Fukumoto, N. Kume, S. Takahashi, J. Yamaguchi, M. Minami, K. Hayashida, T. Kita, J. Ohsumi, et al. Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells J. Leukoc. Biol., February 1, 2004; 75(2): 267 - 274. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Yamauchi, M. Tanaka, N. Kume, M. Minami, T. Kawamoto, K. Togi, T. Shimaoka, S. Takahashi, J. Yamaguchi, T. Nishina, et al. Upregulation of SR-PSOX/CXCL16 and Recruitment of CD8+ T Cells in Cardiac Valves During Inflammatory Valvular Heart Disease Arterioscler Thromb Vasc Biol, February 1, 2004; 24(2): 282 - 287. [Abstract] [Full Text]
|
|
|
|
|
|
B. Chandrasekar, S. Bysani, and S. Mummidi CXCL16 Signals via Gi, Phosphatidylinositol 3-Kinase, Akt, I{kappa}B Kinase, and Nuclear Factor-{kappa}B and Induces Cell-Cell Adhesion and Aortic Smooth Muscle Cell Proliferation J. Biol. Chem., January 30, 2004; 279(5): 3188 - 3196. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ueda, K. Yang, S. J. Foster, M. Kondo, and G. Kelsoe Inflammation Controls B Lymphopoiesis by Regulating Chemokine CXCL12 Expression J. Exp. Med., January 5, 2004; 199(1): 47 - 58. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Johnston, C. H. Kim, D. Soler, M. Emoto, and E. C. Butcher Differential Chemokine Responses and Homing Patterns of Murine TCR{alpha}{beta} NKT Cell Subsets J. Immunol., September 15, 2003; 171(6): 2960 - 2969. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shimaoka, T. Nakayama, N. Kume, S. Takahashi, J. Yamaguchi, M. Minami, K. Hayashida, T. Kita, J. Ohsumi, O. Yoshie, et al. Cutting Edge: SR-PSOX/CXC Chemokine Ligand 16 Mediates Bacterial Phagocytosis by APCs Through its Chemokine Domain J. Immunol., August 15, 2003; 171(4): 1647 - 1651. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Nakayama, K. Hieshima, D. Izawa, Y. Tatsumi, A. Kanamaru, and O. Yoshie Cutting Edge: Profile of Chemokine Receptor Expression on Human Plasma Cells Accounts for Their Efficient Recruitment to Target Tissues J. Immunol., February 1, 2003; 170(3): 1136 - 1140. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Shashkin, D. Simpson, V. Mishin, B. Chesnutt, and K. Ley Expression of CXCL16 in Human T Cells Arterioscler Thromb Vasc Biol, January 1, 2003; 23(1): 148 - 149. [Full Text] [PDF]
|
|
|
|
|
|
C. H. Kim, B. Johnston, and E. C. Butcher Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among Valpha 24+Vbeta 11+ NKT cell subsets with distinct cytokine-producing capacity Blood, June 17, 2002; 100(1): 11 - 16. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Nishimura, H. Umehara, T. Nakayama, O. Yoneda, K. Hieshima, M. Kakizaki, N. Dohmae, O. Yoshie, and T. Imai Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression J. Immunol., June 15, 2002; 168(12): 6173 - 6180. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Murphy International Union of Pharmacology. XXX. Update on Chemokine Receptor Nomenclature Pharmacol. Rev., June 1, 2002; 54(2): 227 - 229. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Balabanian, A. Foussat, P. Dorfmuller, I. Durand-Gasselin, F. Capel, L. Bouchet-Delbos, A. Portier, A. Marfaing-Koka, R. Krzysiek, A.-C. Rimaniol, et al. CX3C Chemokine Fractalkine in Pulmonary Arterial Hypertension Am. J. Respir. Crit. Care Med., May 15, 2002; 165(10): 1419 - 1425. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Hofnagel, B. Luechtenborg, G. Plenz, H. Robenek, and N. Kume Expression of the Novel Scavenger Receptor SR-PSOX in Cultured Aortic Smooth Muscle Cells and Umbilical Endothelial Cells Arterioscler Thromb Vasc Biol, April 1, 2002; 22(4): 710 - 711. [Full Text] [PDF]
|
|
|
|
|
|
M Heydtmann and D H Adams Understanding selective trafficking of lymphocyte subsets Gut, February 1, 2002; 50(2): 150 - 152. [Full Text] [PDF]
|
|
|
|
 |
|
 B. Lee, G. Leslie, E. Soilleux, U. O'Doherty, S. Baik, E. Levroney, K. Flummerfelt, W. Swiggard, N. Coleman, M. Malim, et al. cis Expression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor J. Virol., December 15, 2001; 75(24): 12028 - 12038. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Minami, N. Kume, T. Shimaoka, H. Kataoka, K. Hayashida, Y. Akiyama, I. Nagata, K. Ando, M. Nobuyoshi, M. Hanyuu, et al. Expression of SR-PSOX, a Novel Cell-Surface Scavenger Receptor for Phosphatidylserine and Oxidized LDL in Human Atherosclerotic Lesions Arterioscler Thromb Vasc Biol, November 1, 2001; 21(11): 1796 - 1800. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Campbell, S. Qin, D. Unutmaz, D. Soler, K. E. Murphy, M. R. Hodge, L. Wu, and E. C. Butcher Unique Subpopulations of CD56+ NK and NK-T Peripheral Blood Lymphocytes Identified by Chemokine Receptor Expression Repertoire J. Immunol., June 1, 2001; 166(11): 6477 - 6482. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. S. Mizoue, S. K. Sullivan, D. S. King, T. N. Kledal, T. W. Schwartz, K. B. Bacon, and T. M. Handel Molecular Determinants of Receptor Binding and Signaling by the CX3C Chemokine Fractalkine J. Biol. Chem., August 31, 2001; 276(36): 33906 - 33914. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
