| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
*
The Rockefeller University, New York, NY 10021; and
The Virogenetics Corporation, Troy, NY
Vaccinia virus employs multiple mechanisms to evade the immune system, yet is highly immunogenic. We studied the interaction between vaccinia and human dendritic cells (DCs), potent APCs. DCs develop from precursor cells in two stages: an immature stage in which Ag uptake and processing occur, and a mature stage in which there is up-regulation of costimulatory and HLA molecules and efficient T cell activation. Vaccinia virus undergoes an abortive replication in both stages of DCs and induces apoptotic cell death. Furthermore, maturation of immature DCs and consequently T cell activation are inhibited. Obstruction of DC maturation may constitute a novel mechanism by which vaccinia attempts to evade the immune response.
This article has been cited by other articles:
|
|
 |
|
  R. Rahbar, T. T. Murooka, and E. N. Fish Role for CCR5 in Dissemination of Vaccinia Virus In Vivo J. Virol., March 1, 2009; 83(5): 2226 - 2236. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Waibler, M. Anzaghe, T. Frenz, A. Schwantes, C. Pohlmann, H. Ludwig, M. Palomo-Otero, A. Alcami, G. Sutter, and U. Kalinke Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components J. Virol., February 15, 2009; 83(4): 1563 - 1571. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. Mott and H. Ghiasi Role of Dendritic Cells in Enhancement of Herpes Simplex Virus Type 1 Latency and Reactivation in Vaccinated Mice Clin. Vaccine Immunol., December 1, 2008; 15(12): 1859 - 1867. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Arimilli, J. B. Johnson, K. M. Clark, A. H. Graff, M. A. Alexander-Miller, S. B. Mizel, and G. D. Parks Engineered Expression of the TLR5 Ligand Flagellin Enhances Paramyxovirus Activation of Human Dendritic Cell Function J. Virol., November 15, 2008; 82(22): 10975 - 10985. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Prestwich, F. Errington, E. J. Ilett, R. S.M. Morgan, K. J. Scott, T. Kottke, J. Thompson, E. E. Morrison, K. J. Harrington, H. S. Pandha, et al. Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity Clin. Cancer Res., November 15, 2008; 14(22): 7358 - 7366. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Dejnirattisai, T. Duangchinda, C.-L. S. Lin, S. Vasanawathana, M. Jones, M. Jacobs, P. Malasit, X.-n. Xu, G. Screaton, and J. Mongkolsapaya A Complex Interplay among Virus, Dendritic Cells, T Cells, and Cytokines in Dengue Virus Infections J. Immunol., November 1, 2008; 181(9): 5865 - 5874. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. R. Mott, D. UnderHill, S. L. Wechsler, and H. Ghiasi Lymphoid-Related CD11c+ CD8{alpha}+ Dendritic Cells Are Involved in Enhancing Herpes Simplex Virus Type 1 Latency J. Virol., October 15, 2008; 82(20): 9870 - 9879. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. M. Melhem, S. M. Gleason, X. D. Liu, and S. M. Barratt-Boyes High-Level Antigen Expression and Sustained Antigen Presentation in Dendritic Cells Nucleofected with Wild-Type Viral mRNA but Not DNA Clin. Vaccine Immunol., September 1, 2008; 15(9): 1337 - 1344. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Parker, W. M. Yokoyama, J. A. Corbett, N. Chen, and R. M. L. Buller Primary naive and interleukin-2-activated natural killer cells do not support efficient ectromelia virus replication J. Gen. Virol., March 1, 2008; 89(3): 751 - 759. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Landi, L. A. Babiuk, and S. van Drunen Littel-van den Hurk High transfection efficiency, gene expression, and viability of monocyte-derived human dendritic cells after nonviral gene transfer J. Leukoc. Biol., October 1, 2007; 82(4): 849 - 860. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Guerra, J. L. Najera, J. M. Gonzalez, L. A. Lopez-Fernandez, N. Climent, J. M. Gatell, T. Gallart, and M. Esteban Distinct Gene Expression Profiling after Infection of Immature Human Monocyte-Derived Dendritic Cells by the Attenuated Poxvirus Vectors MVA and NYVAC J. Virol., August 15, 2007; 81(16): 8707 - 8721. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Hochreiter, C. Ptaschinski, S. L. Kunkel, and R. Rochford Murine gammaherpesvirus-68 productively infects immature dendritic cells and blocks maturation J. Gen. Virol., July 1, 2007; 88(7): 1896 - 1905. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Perreau, F. Mennechet, N. Serratrice, J. N. Glasgow, D. T. Curiel, H. Wodrich, and E. J. Kremer Contrasting Effects of Human, Canine, and Hybrid Adenovirus Vectors on the Phenotypical and Functional Maturation of Human Dendritic Cells: Implications for Clinical Efficacy J. Virol., April 1, 2007; 81(7): 3272 - 3284. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Mintern, E. J. Klemm, M. Wagner, M. E. Paquet, M. D. Napier, Y. M. Kim, U. H. Koszinowski, and H. L. Ploegh Viral Interference with B7-1 Costimulation: A New Role for Murine Cytomegalovirus Fc Receptor-1 J. Immunol., December 15, 2006; 177(12): 8422 - 8431. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. N. Harman, J. Wilkinson, C. R. Bye, L. Bosnjak, J. L. Stern, M. Nicholle, J. Lai, and A. L. Cunningham HIV Induces Maturation of Monocyte-Derived Dendritic Cells and Langerhans Cells J. Immunol., November 15, 2006; 177(10): 7103 - 7113. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Deng, P. Dai, W. Ding, R. D. Granstein, and S. Shuman Vaccinia Virus Infection Attenuates Innate Immune Responses and Antigen Presentation by Epidermal Dendritic Cells J. Virol., October 15, 2006; 80(20): 9977 - 9987. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Chahroudi, D. A. Garber, P. Reeves, L. Liu, D. Kalman, and M. B. Feinberg Differences and Similarities in Viral Life Cycle Progression and Host Cell Physiology after Infection of Human Dendritic Cells with Modified Vaccinia Virus Ankara and Vaccinia Virus J. Virol., September 1, 2006; 80(17): 8469 - 8481. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Shi and J. Xiang CD4+ T cell-independent maintenance and expansion of memory CD8+ T cells derived from in vitro dendritic cell activation Int. Immunol., June 1, 2006; 18(6): 887 - 895. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Arimilli, M. A. Alexander-Miller, and G. D. Parks A Simian Virus 5 (SV5) P/V Mutant Is Less Cytopathic than Wild-Type SV5 in Human Dendritic Cells and Is a More Effective Activator of Dendritic Cell Maturation and Function J. Virol., April 1, 2006; 80(7): 3416 - 3427. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Thiele, T. L. Sumpter, J. A. Walker, Q. Xu, C.-H. Chang, R. L. Bacallao, R. Kher, and D. S. Wilkes Pulmonary Immunity to Viral Infection: Adenovirus Infection of Lung Dendritic Cells Renders T Cells Nonresponsive to Interleukin-2 J. Virol., February 15, 2006; 80(4): 1826 - 1836. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. F. Narvaez, J. Angel, and M. A. Franco Interaction of Rotavirus with Human Myeloid Dendritic Cells J. Virol., December 1, 2005; 79(23): 14526 - 14535. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Li, N. Wang, D. Zhou, C. S. K. Yee, C.-H. Chang, R. R. Brutkiewicz, and J. S. Blum Disruption of MHC Class II-Restricted Antigen Presentation by Vaccinia Virus J. Immunol., November 15, 2005; 175(10): 6481 - 6488. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Bosio and S. W. Dow Francisella tularensis Induces Aberrant Activation of Pulmonary Dendritic Cells J. Immunol., November 15, 2005; 175(10): 6792 - 6801. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. A. de Graaff, E. C. de Jong, T. M. van Capel, M. E. A. van Dijk, P. J. M. Roholl, J. Boes, W. Luytjes, J. L. L. Kimpen, and G. M. van Bleek Respiratory Syncytial Virus Infection of Monocyte-Derived Dendritic Cells Decreases Their Capacity to Activate CD4 T Cells J. Immunol., November 1, 2005; 175(9): 5904 - 5911. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Esteban and R. M. L. Buller Ectromelia virus: the causative agent of mousepox J. Gen. Virol., October 1, 2005; 86(10): 2645 - 2659. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ostrowski, M. Vermeulen, O. Zabal, J. R. Geffner, A. M. Sadir, and O. J. Lopez Impairment of Thymus-Dependent Responses by Murine Dendritic Cells Infected with Foot-and-Mouth Disease Virus J. Immunol., September 15, 2005; 175(6): 3971 - 3979. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Flano, B. Kayhan, D. L. Woodland, and M. A. Blackman Infection of Dendritic Cells by a {gamma}2-Herpesvirus Induces Functional Modulation J. Immunol., September 1, 2005; 175(5): 3225 - 3234. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Chahroudi, R. Chavan, N. Koyzr, E. K. Waller, G. Silvestri, and M. B. Feinberg Vaccinia Virus Tropism for Primary Hematolymphoid Cells Is Determined by Restricted Expression of a Unique Virus Receptor J. Virol., August 15, 2005; 79(16): 10397 - 10407. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Liu, Z. Xu, R. C. Fuhlbrigge, V. Pena-Cruz, J. Lieberman, and T. S. Kupper Vaccinia Virus Induces Strong Immunoregulatory Cytokine Production in Healthy Human Epidermal Keratinocytes: a Novel Strategy for Immune Evasion J. Virol., June 15, 2005; 79(12): 7363 - 7370. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. G. Shannon, D. Howe, and R. A. Heinzen Virulent Coxiella burnetii does not activate human dendritic cells: Role of lipopolysaccharide as a shielding molecule PNAS, June 14, 2005; 102(24): 8722 - 8727. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Prechtel, N. M. Turza, D. J. Kobelt, J. I. Eisemann, R. S. Coffin, Y. McGrath, C. Hacker, X. Ju, M. Zenke, and A. Steinkasserer Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration J. Gen. Virol., June 1, 2005; 86(6): 1645 - 1657. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Bousarghin, P. Hubert, E. Franzen, N. Jacobs, J. Boniver, and P. Delvenne Human papillomavirus 16 virus-like particles use heparan sulfates to bind dendritic cells and colocalize with langerin in Langerhans cells J. Gen. Virol., May 1, 2005; 86(5): 1297 - 1305. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Muraro, A. Bondanza, M. Bellone, P. D. Greenberg, and C. Bonini Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses Blood, May 1, 2005; 105(9): 3596 - 3604. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Beuria, H. Chen, M. Timoney, and K. Sperber Impaired Accessory Cell Function in a Human Dendritic Cell Line after Human Immunodeficiency Virus Infection Clin. Vaccine Immunol., March 1, 2005; 12(3): 453 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Chen, C. Barnfield, T. I. Naslund, M. N. Fleeton, and P. Liljestrom MyD88 Expression Is Required for Efficient Cross-Presentation of Viral Antigens from Infected Cells J. Virol., March 1, 2005; 79(5): 2964 - 2972. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. N. J. Bullock and H. Yagita Induction of CD70 on Dendritic Cells through CD40 or TLR Stimulation Contributes to the Development of CD8+ T Cell Responses in the Absence of CD4+ T Cells J. Immunol., January 15, 2005; 174(2): 710 - 717. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Wilflingseder, B. Mullauer, H. Schramek, Z. Banki, M. Pruenster, M. P. Dierich, and H. Stoiber HIV-1-Induced Migration of Monocyte-Derived Dendritic Cells Is Associated with Differential Activation of MAPK Pathways J. Immunol., December 15, 2004; 173(12): 7497 - 7505. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Tavakoli, W. Schwerin, A. Rohwer, S. Hoffmann, S. Weyer, R. Weth, H. Meisel, H. Diepolder, M. Geissler, P. R. Galle, et al. Phenotype and function of monocyte derived dendritic cells in chronic hepatitis B virus infection J. Gen. Virol., October 1, 2004; 85(10): 2829 - 2836. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Fantuzzi, C. Purificato, K. Donato, F. Belardelli, and S. Gessani Human Immunodeficiency Virus Type 1 gp120 Induces Abnormal Maturation and Functional Alterations of Dendritic Cells: a Novel Mechanism for AIDS Pathogenesis J. Virol., September 15, 2004; 78(18): 9763 - 9772. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Tobar, P. A. Gonzalez, and A. M. Kalergis Salmonella Escape from Antigen Presentation Can Be Overcome by Targeting Bacteria to Fc{gamma} Receptors on Dendritic Cells J. Immunol., September 15, 2004; 173(6): 4058 - 4065. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. L. W. Chang, N. Baumgarth, D. Yu, and P. A. Barry Human Cytomegalovirus-Encoded Interleukin-10 Homolog Inhibits Maturation of Dendritic Cells and Alters Their Functionality J. Virol., August 15, 2004; 78(16): 8720 - 8731. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Zinser, M. Lechmann, A. Golka, M. B. Lutz, and A. Steinkasserer Prevention and Treatment of Experimental Autoimmune Encephalomyelitis by Soluble CD83 J. Exp. Med., August 2, 2004; 200(3): 345 - 351. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Drillien, D. Spehner, and D. Hanau Modified vaccinia virus Ankara induces moderate activation of human dendritic cells J. Gen. Virol., August 1, 2004; 85(8): 2167 - 2175. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Teleshova, J. Kenney, J. Jones, J. Marshall, G. Van Nest, J. Dufour, R. Bohm, J. D. Lifson, A. Gettie, and M. Pope CpG-C Immunostimulatory Oligodeoxyribonucleotide Activation of Plasmacytoid Dendritic Cells in Rhesus Macaques to Augment the Activation of IFN-{gamma}-Secreting Simian Immunodeficiency Virus-Specific T Cells J. Immunol., August 1, 2004; 173(3): 1647 - 1657. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Granelli-Piperno, A. Golebiowska, C. Trumpfheller, F. P. Siegal, and R. M. Steinman HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation PNAS, May 18, 2004; 101(20): 7669 - 7674. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. C. Turner, E. M. Hemmila, N. Beauchemin, and K. V. Holmes Receptor-Dependent Coronavirus Infection of Dendritic Cells J. Virol., May 15, 2004; 78(10): 5486 - 5490. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Gelman, J. Zhang, Y. Choi, and L. A. Turka Toll-Like Receptor Ligands Directly Promote Activated CD4+ T Cell Survival J. Immunol., May 15, 2004; 172(10): 6065 - 6073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. T. Semnani, M. Law, J. Kubofcik, and T. B. Nutman Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface J. Immunol., May 15, 2004; 172(10): 6229 - 6238. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Tuettenberg, H. Jonuleit, T. Tuting, J. Bruck, V. Biermann, S. Kochanek, J. Knop, and A. H. Enk Early Adenoviral Gene Expression Mediates Immunosuppression by Transduced Dendritic Cell (DC): Implications for Immunotherapy Using Genetically Modified DC J. Immunol., February 1, 2004; 172(3): 1524 - 1530. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kikuchi, T. Kobayashi, K. Gomi, T. Suzuki, Y. Tokue, A. Watanabe, and T. Nukiwa Dendritic Cells Pulsed with Live and Dead Legionella pneumophila Elicit Distinct Immune Responses J. Immunol., February 1, 2004; 172(3): 1727 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Taylor, T. A. Haigh, N. H. Gudgeon, R. J. Phelps, S. P. Lee, N. M. Steven, and A. B. Rickinson Dual Stimulation of Epstein-Barr Virus (EBV)-Specific CD4+- and CD8+-T-Cell Responses by a Chimeric Antigen Construct: Potential Therapeutic Vaccine for EBV-Positive Nasopharyngeal Carcinoma J. Virol., January 15, 2004; 78(2): 768 - 778. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. E. Vincent, C. P. Carrasco, B. Herrmann, B. M. Meehan, G. M. Allan, A. Summerfield, and K. C. McCullough Dendritic Cells Harbor Infectious Porcine Circovirus Type 2 in the Absence of Apparent Cell Modulation or Replication of the Virus J. Virol., December 15, 2003; 77(24): 13288 - 13300. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Fonteneau, D. G. Kavanagh, M. Lirvall, C. Sanders, T. L. Cover, N. Bhardwaj, and M. Larsson Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells Blood, December 15, 2003; 102(13): 4448 - 4455. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Sarobe, J. J. Lasarte, A. Zabaleta, L. Arribillaga, A. Arina, I. Melero, F. Borras-Cuesta, and J. Prieto Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses J. Virol., October 15, 2003; 77(20): 10862 - 10871. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Gredmark and C. Soderberg-Naucler Human Cytomegalovirus Inhibits Differentiation of Monocytes into Dendritic Cells with the Consequence of Depressed Immunological Functions J. Virol., October 15, 2003; 77(20): 10943 - 10956. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Wang, M. Messerle, R. Sapinoro, K. Santos, P. K. Hocknell, X. Jin, and S. Dewhurst Murine Cytomegalovirus Abortively Infects Human Dendritic Cells, Leading to Expression and Presentation of Virally Vectored Genes J. Virol., July 1, 2003; 77(13): 7182 - 7192. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Vezys and L. Lefrancois Cutting Edge: Inflammatory Signals Drive Organ-Specific Autoimmunity to Normally Cross-Tolerizing Endogenous Antigen J. Immunol., December 15, 2002; 169(12): 6677 - 6680. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Humlova, M. Vokurka, M. Esteban, and Z. Melkova Vaccinia virus induces apoptosis of infected macrophages J. Gen. Virol., November 1, 2002; 83(11): 2821 - 2832. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Hel, J. Nacsa, E. Tryniszewska, W.-P. Tsai, R. W. Parks, D. C. Montefiori, B. K. Felber, J. Tartaglia, G. N. Pavlakis, and G. Franchini Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4+ and CD8+ T Cell Responses J. Immunol., November 1, 2002; 169(9): 4778 - 4787. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kakimoto, A. Hasegawa, S. Fujita, and M. Yasukawa Phenotypic and Functional Alterations of Dendritic Cells Induced by Human Herpesvirus 6 Infection J. Virol., October 15, 2002; 76(20): 10338 - 10345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. V. Overtvelt, M. Andrieu, V. Verhasselt, F. Connan, J. Choppin, V. Vercruysse, M. Goldman, A. Hosmalin, and B. Vray Trypanosoma cruzi down-regulates lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8+ T lymphocytes Int. Immunol., October 1, 2002; 14(10): 1135 - 1144. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. C. Fausch, D. M. Da Silva, M. P. Rudolf, and W. M. Kast Human Papillomavirus Virus-Like Particles Do Not Activate Langerhans Cells: A Possible Immune Escape Mechanism Used by Human Papillomaviruses J. Immunol., September 15, 2002; 169(6): 3242 - 3249. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Currier, M. deSouza, P. Chanbancherd, W. Bernstein, D. L. Birx, and J. H. Cox Comprehensive Screening for Human Immunodeficiency Virus Type 1 Subtype-Specific CD8 Cytotoxic T Lymphocytes and Definition of Degenerate Epitopes Restricted by HLA-A0207 and -CW0304 Alleles J. Virol., May 15, 2002; 76(10): 4971 - 4986. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Sarobe, J. J. Lasarte, N. Casares, A. Lopez-Diaz de Cerio, E. Baixeras, P. Labarga, N. Garcia, F. Borras-Cuesta, and J. Prieto Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins J. Virol., May 15, 2002; 76(10): 5062 - 5070. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Li, D. Liu, L. Hutt-Fletcher, A. Morgan, M. G. Masucci, and V. Levitsky Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage-colony-stimulating factor and interleukin-4 Blood, May 15, 2002; 99(10): 3725 - 3734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Moutaftsi, A. M. Mehl, L. K. Borysiewicz, and Z. Tabi Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells Blood, April 15, 2002; 99(8): 2913 - 2921. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Lechmann, D. J.E.B. Krooshoop, D. Dudziak, E. Kremmer, C. Kuhnt, C. G. Figdor, G. Schuler, and A. Steinkasserer The Extracellular Domain of CD83 Inhibits Dendritic Cell-mediated T Cell Stimulation and Binds to a Ligand on Dendritic Cells J. Exp. Med., December 17, 2001; 194(12): 1813 - 1821. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Hel, W.-P. Tsai, A. Thornton, J. Nacsa, L. Giuliani, E. Tryniszewska, M. Poudyal, D. Venzon, X. Wang, J. Altman, et al. Potentiation of Simian Immunodeficiency Virus (SIV)-Specific CD4+ and CD8+ T Cell Responses by a DNA-SIV and NYVAC-SIV Prime/Boost Regimen J. Immunol., December 15, 2001; 167(12): 7180 - 7191. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. W. Cutler, R. Jotwani, and B. Pulendran Dendritic Cells: Immune Saviors or Achilles' Heel? Infect. Immun., August 1, 2001; 69(8): 4703 - 4708. [Full Text] [PDF]
|
|
|
|
|
|
Z. Mikloska, L. Bosnjak, and A. L. Cunningham Immature Monocyte-Derived Dendritic Cells Are Productively Infected with Herpes Simplex Virus Type 1 J. Virol., July 1, 2001; 75(13): 5958 - 5964. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. P. Rudolf, S. C. Fausch, D. M. Da Silva, and W. M. Kast Human Dendritic Cells Are Activated by Chimeric Human Papillomavirus Type-16 Virus-Like Particles and Induce Epitope-Specific Human T Cell Responses In Vitro J. Immunol., May 15, 2001; 166(10): 5917 - 5924. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lenz, P. M. Day, Y.-Y. S. Pang, S. A. Frye, P. N. Jensen, D. R. Lowy, and J. T. Schiller Papillomavirus-Like Particles Induce Acute Activation of Dendritic Cells J. Immunol., May 1, 2001; 166(9): 5346 - 5355. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Bonini, S. P. Lee, S. R. Riddell, and P. D. Greenberg Targeting Antigen in Mature Dendritic Cells for Simultaneous Stimulation of CD4+ and CD8+ T Cells J. Immunol., April 15, 2001; 166(8): 5250 - 5257. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Engelmayer, M. Larsson, A. Lee, M. Lee, W. I. Cox, R. M. Steinman, and N. Bhardwaj Mature Dendritic Cells Infected with Canarypox Virus Elicit Strong Anti-Human Immunodeficiency Virus CD8+ and CD4+ T-Cell Responses from Chronically Infected Individuals J. Virol., March 1, 2001; 75(5): 2142 - 2153. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L.-J. Ho, J.-J. Wang, M.-F. Shaio, C.-L. Kao, D.-M. Chang, S.-W. Han, and J.-H. Lai Infection of Human Dendritic Cells by Dengue Virus Causes Cell Maturation and Cytokine Production J. Immunol., February 1, 2001; 166(3): 1499 - 1506. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Gardner, I. Frolov, S. Perri, Y. Ji, M. L. MacKichan, J. zur Megede, M. Chen, B. A. Belli, D. A. Driver, S. Sherrill, et al. Infection of Human Dendritic Cells by a Sindbis Virus Replicon Vector Is Determined by a Single Amino Acid Substitution in the E2 Glycoprotein J. Virol., December 15, 2000; 74(24): 11849 - 11857. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Ignatius, M. Marovich, E. Mehlhop, L. Villamide, K. Mahnke, W. I. Cox, F. Isdell, S. S. Frankel, J. R. Mascola, R. M. Steinman, et al. Canarypox Virus-Induced Maturation of Dendritic Cells Is Mediated by Apoptotic Cell Death and Tumor Necrosis Factor Alpha Secretion J. Virol., December 1, 2000; 74(23): 11329 - 11338. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Granelli-Piperno, L. Zhong, P. Haslett, J. Jacobson, and R. M. Steinman Dendritic Cells, Infected with Vesicular Stomatitis Virus-Pseudotyped HIV-1, Present Viral Antigens to CD4+ and CD8+ T Cells from HIV-1-Infected Individuals J. Immunol., December 1, 2000; 165(11): 6620 - 6626. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Meyer zum Buschenfelde, N. Nicklisch, S. Rose-John, C. Peschel, and H. Bernhard Generation of Tumor-Reactive CTL Against the Tumor-Associated Antigen HER2 Using Retrovirally Transduced Dendritic Cells Derived from CD34+ Hemopoietic Progenitor Cells J. Immunol., October 1, 2000; 165(7): 4133 - 4140. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kruse, O. Rosorius, F. Kratzer, G. Stelz, C. Kuhnt, G. Schuler, J. Hauber, and A. Steinkasserer Mature Dendritic Cells Infected with Herpes Simplex Virus Type 1 Exhibit Inhibited T-Cell Stimulatory Capacity J. Virol., August 1, 2000; 74(15): 7127 - 7136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. S. Subauste and M. Wessendarp Human Dendritic Cells Discriminate Between Viable and Killed Toxoplasma gondii Tachyzoites: Dendritic Cell Activation After Infection with Viable Parasites Results in CD28 and CD40 Ligand Signaling That Controls IL-12-Dependent and -Independent T Cell Production of IFN-{gamma} J. Immunol., August 1, 2000; 165(3): 1498 - 1505. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Munz, K. L. Bickham, M. Subklewe, M. L. Tsang, A. Chahroudi, M. G. Kurilla, D. Zhang, M. O'Donnell, and R. M. Steinman Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1 J. Exp. Med., May 15, 2000; 191(10): 1649 - 1660. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Berwin, R. C. Reed, and C. V. Nicchitta Virally Induced Lytic Cell Death Elicits the Release of Immunogenic GRP94/gp96 J. Biol. Chem., June 8, 2001; 276(24): 21083 - 21088. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
