HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ramsdell, S. G. Search for Related Content PubMed Articles by Ramsdell, S. G.

The Skin Reaction in the Sensitized Guinea Pig

From Research Institute of Cutaneous Medicine, Philadelphia, Pennsylvania

Abstract

Guinea pigs actively sensitized and skin-tested, using trypan blue as a technical aid, gave reactions to the antigen-serum in dilutions as high as 1:10,000. Passive sensitization of the skin of a normal animal could be demonstrated as early as the sixth day after treatment of the actively sensitized animal, and was regularly more consistent than the test for passive sensitization by shock. Whether the antibody responsible for the skin reaction is a separate one from the anaphylactic antibody or merely an extension of its manifestation is not clear.