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Qualitative Diversity of Agglutinin Response Among Different Rabbits Treated with the Same Complex Antigen (Streptococcus Scarlatin æ)

From the Department of Immunology, Evans Memorial, Boston

Abstract

The results suggest that qualitative deficiency of antibody response to scarlatinal streptococci occurs rather infrequently among rabbits. It probably explains some of the discrepant reactions obtained by different investigators who have worked with the same strains. The fact that an immune serum may not faithfully and completely reflect the antigenic features of a complex inoculum receives additional confirmation as does our previous conclusion that the injected animal's individuality may constitute an important variable in experiments of this kind.