The JI Acurri Cytometers
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dohring, C
Right arrow Articles by Colonna, M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dohring, C
Right arrow Articles by Colonna, M

The Journal of Immunology, Vol 156, Issue 9 3098-3101, Copyright © 1996 by American Association of Immunologists

CUTTING EDGE

A human killer inhibitory receptor specific for HLA-A1,2

C Dohring, D Scheidegger, J Samaridis, M Cella and M Colonna
Basel Institute for Immunology, Switzerland.

Killer inhibitory receptors (KIRs) are transmembrane glycoproteins, expressed on NK cells and a small subset of T cells, that inhibit cell- mediated cytotoxicity upon binding to polymorphic MHC class I determinants on target cells. Although human KIRs specific for HLA-C and HLA-B molecules have been characterized, none have been shown to interact with HLA-A. Here we demonstrate that a member of the KIR cDNA family, designated NKAT4, encodes a 70-kDa receptor specific for HLA-A3.


This article has been cited by other articles:


Home page
 J. Immunol.Home page
E. Estefania, R. Flores, N. Gomez-Lozano, H. Aguilar, M. Lopez-Botet, and C. Vilches
Human KIR2DL5 Is an Inhibitory Receptor Expressed on the Surface of NK and T Lymphocyte Subsets
J. Immunol., April 1, 2007; 178(7): 4402 - 4410.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
G. Betser-Cohen, G. Katz, T. Gonen-Gross, N. Stern, T. I. Arnon, H. Achdout, R. Gazit, and O. Mandelboim
Reduced KIR2DL1 Recognition of MHC Class I Molecules Presenting Phosphorylated Peptides.
J. Immunol., June 1, 2006; 176(11): 6762 - 6769.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
A. A. Maghazachi
Insights into Seven and Single Transmembrane-Spanning Domain Receptors and Their Signaling Pathways in Human Natural Killer Cells
Pharmacol. Rev., September 1, 2005; 57(3): 339 - 357.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Interv.Home page
A. P. Williams, A. R. Bateman, and S. I. Khakoo
HANGING IN THE BALANCE: KIR and Their Role in Disease
Mol. Interv., August 1, 2005; 5(4): 226 - 240.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
C. Brando, S. Mukhopadhyay, E. Kovacs, R. Medina, P. Patel, T. L. Catina, K. S. Campbell, and D. Santoli
Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104
J. Leukoc. Biol., August 1, 2005; 78(2): 359 - 371.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
B.-C. Sheu, S.-H. Chiou, H.-H. Lin, S.-N. Chow, S.-C. Huang, H.-N. Ho, and S.-M. Hsu
Up-regulation of Inhibitory Natural Killer Receptors CD94/NKG2A with Suppressed Intracellular Perforin Expression of Tumor-Infiltrating CD8+ T Lymphocytes in Human Cervical Carcinoma
Cancer Res., April 1, 2005; 65(7): 2921 - 2929.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. Draghi, N. Yawata, M. Gleimer, M. Yawata, N. M. Valiante, and P. Parham
Single-cell analysis of the human NK cell response to missing self and its inhibition by HLA class I
Blood, March 1, 2005; 105(5): 2028 - 2035.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
W. Leung, R. Iyengar, V. Turner, P. Lang, P. Bader, P. Conn, D. Niethammer, and R. Handgretinger
Determinants of Antileukemia Effects of Allogeneic NK Cells
J. Immunol., January 1, 2004; 172(1): 644 - 650.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
C. Pridgeon, G. P. Lennon, L. Pazmany, R. N. Thompson, S. E. Christmas, and R. J. Moots
Natural killer cells in the synovial fluid of rheumatoid arthritis patients exhibit a CD56bright,CD94bright,CD158negative phenotype
Rheumatology, July 1, 2003; 42(7): 870 - 878.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Santourlidis, H.-I. Trompeter, S. Weinhold, B. Eisermann, K. L. Meyer, P. Wernet, and M. Uhrberg
Crucial Role of DNA Methylation in Determination of Clonally Distributed Killer Cell Ig-like Receptor Expression Patterns in NK Cells
J. Immunol., October 15, 2002; 169(8): 4253 - 4261.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
S. I. Khakoo, R. Geller, S. Shin, J. A. Jenkins, and P. Parham
The D0 Domain of KIR3D Acts as a Major Histocompatibility Complex Class I Binding Enhancer
J. Exp. Med., October 7, 2002; 196(7): 911 - 921.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
S. S. Farag, T. A. Fehniger, L. Ruggeri, A. Velardi, and M. A. Caligiuri
Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect
Blood, August 28, 2002; 100(6): 1935 - 1947.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
H. G. Shilling, L. A. Guethlein, N. W. Cheng, C. M. Gardiner, R. Rodriguez, D. Tyan, and P. Parham
Allelic Polymorphism Synergizes with Variable Gene Content to Individualize Human KIR Genotype
J. Immunol., March 1, 2002; 168(5): 2307 - 2315.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
E. J. Adams, S. Cooper, and P. Parham
A Novel, Nonclassical MHC Class I Molecule Specific to the Common Chimpanzee
J. Immunol., October 1, 2001; 167(7): 3858 - 3869.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Uhrberg, N. M. Valiante, N. T. Young, L. L. Lanier, J. H. Phillips, and P. Parham
The Repertoire of Killer Cell Ig-Like Receptor and CD94:NKG2A Receptors in T Cells: Clones Sharing Identical {{alpha}}{{beta}} TCR Rearrangement Express Highly Diverse Killer Cell Ig-Like Receptor Patterns
J. Immunol., March 15, 2001; 166(6): 3923 - 3932.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
C. M. Gardiner, L. A. Guethlein, H. G. Shilling, M. Pando, W. H. Carr, R. Rajalingam, C. Vilches, and P. Parham
Different NK Cell Surface Phenotypes Defined by the DX9 Antibody Are Due to KIR3DL1 Gene Polymorphism
J. Immunol., March 1, 2001; 166(5): 2992 - 3001.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. Bagot, A. Moretta, S. Sivori, R. Biassoni, C. Cantoni, C. Bottino, L. Boumsell, and A. Bensussan
CD4+ cutaneous T-cell lymphoma cells express the p140-killer cell immunoglobulin-like receptor
Blood, March 1, 2001; 97(5): 1388 - 1391.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
F. Vely, M.-A. Peyrat, C. Couedel, J.-F. Morcet, F. Halary, F. Davodeau, F. Romagne, E. Scotet, X. Saulquin, E. Houssaint, et al.
Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements
J. Immunol., February 15, 2001; 166(4): 2487 - 2494.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
R. Rajalingam, M. Hong, E. J. Adams, B. P. Shum, L. A. Guethlein, and P. Parham
Short KIR Haplotypes in Pygmy Chimpanzee (Bonobo) Resemble the Conserved Framework of Diverse Human KIR Haplotypes
J. Exp. Med., January 2, 2001; 193(1): 135 - 146.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
C. Vilches, R. Rajalingam, M. Uhrberg, C. M. Gardiner, N. T. Young, and P. Parham
KIR2DL5, a Novel Killer-Cell Receptor with a D0-D2 Configuration of Ig-Like Domains
J. Immunol., June 1, 2000; 164(11): 5797 - 5804.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
D. Pende, S. Parolini, A. Pessino, S. Sivori, R. Augugliaro, L. Morelli, E. Marcenaro, L. Accame, A. Malaspina, R. Biassoni, et al.
Identification and Molecular Characterization of NKp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells
J. Exp. Med., November 15, 1999; 190(10): 1505 - 1516.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Ponte, C. Cantoni, R. Biassoni, A. Tradori-Cappai, G. Bentivoglio, C. Vitale, S. Bertone, A. Moretta, L. Moretta, and M. C. Mingari
Inhibitory receptors sensing HLA-G1 molecules in pregnancy: Decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor
PNAS, May 11, 1999; 96(10): 5674 - 5679.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
S. Rajagopalan and E. O. Long
A Human Histocompatibility Leukocyte Antigen (HLA)-G-specific Receptor Expressed on All Natural Killer Cells
J. Exp. Med., April 5, 1999; 189(7): 1093 - 1100.
[Abstract] [Full Text] [PDF]

Home page
 CVIHome page
E. Mavoungou, A. Sall, V. Poaty-Mavoungou, F. S. Toure, P. Yaba, A. Delicat, and J. Lansoud-Soukate
Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex
Clin. Vaccine Immunol., March 1, 1999; 6(2): 254 - 259.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
M. Vitale, R. Castriconi, S. Parolini, D. Pende, M.-L. Hsu, L. Moretta, D. Cosman, and A. Moretta
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1+ NK cell clones
Int. Immunol., January 1, 1999; 11(1): 29 - 35.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Vales-Gomez, H. T. Reyburn, R. A. Erskine, and J. Strominger
Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
PNAS, November 24, 1998; 95(24): 14326 - 14331.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. Sundback, M. C. Nakamura, M. Waldenstrom, E. C. Niemi, W. E. Seaman, J. C. Ryan, and K. Karre
The {alpha}2 Domain of H-2Dd Restricts the Allelic Specificity of the Murine NK Cell Inhibitory Receptor Ly-49A
J. Immunol., June 15, 1998; 160(12): 5971 - 5978.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Z. B. Kurago, C. T. Lutz, K. D. Smith, and M. Colonna
NK Cell Natural Cytotoxicity and IFN-{gamma} Production Are Not Always Coordinately Regulated: Engagement of DX9 KIR+ NK Cells by HLA-B7 Variants and Target Cells
J. Immunol., February 15, 1998; 160(4): 1573 - 1580.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
I. Carena, A. Shamshiev, A. Donda, M. Colonna, and G. D. Libero
Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor-gamma /delta Stimulated by Nonpeptidic Ligands
J. Exp. Med., November 17, 1997; 186(10): 1769 - 1774.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
M. Cella, C. Dohring, J. Samaridis, M. Dessing, M. Brockhaus, A. Lanzavecchia, and M. Colonna
A Novel Inhibitory Receptor (ILT3) Expressed on Monocytes, Macrophages, and Dendritic Cells Involved in Antigen Processing
J. Exp. Med., May 19, 1997; 185(10): 1743 - 1751.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
O. Mandelboim, S. B. Wilson, M. Vales-Gomez, H. T. Reyburn, and J. L. Strominger
Self and viral peptides can initiate lysis by autologous natural killer cells
PNAS, April 29, 1997; 94(9): 4604 - 4609.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
S. Rajagopalan and E. O. Long
The Direct Binding of a p58 Killer Cell Inhibitory Receptor to Human Histocompatibility Leukocyte Antigen (HLA)-Cw4 Exhibits Peptide Selectivity
J. Exp. Med., April 21, 1997; 185(8): 1523 - 1528.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Blery, J. Delon, A. Trautmann, A. Cambiaggi, L. Olcese, R. Biassoni, L. Moretta, P. Chavrier, A. Moretta, M. Daeron, et al.
Reconstituted Killer Cell Inhibitory Receptors for Major Histocompatibility Complex Class I Molecules Control Mast Cell Activation Induced via Immunoreceptor Tyrosine-based Activation Motifs
J. Biol. Chem., April 4, 1997; 272(14): 8989 - 8996.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
C. Munz, N. Holmes, A. King, Y. W. Loke, M. Colonna, H. Schild, and H.-G. Rammensee
Human Histocompatibility Leukocyte Antigen (HLA)-G Molecules Inhibit NKAT3 Expressing Natural Killer Cells
J. Exp. Med., February 3, 1997; 185(3): 385 - 392.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1996 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1996 by The American Association of Immunologists, Inc. All rights reserved.