| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Immunology, Vol 156, Issue 12 4531-4534, Copyright © 1996 by American Association of Immunologists
CUTTING EDGE |
L Olcese, P Lang, F Vely, A Cambiaggi, D Marguet, M Blery, KL Hippen, R Biassoni, A Moretta, L Moretta, JC Cambier and E Vivier
Center for Immunology, INSERM/CNRS of Marseille-Luminy, France.
NK cells express cell surface receptors for MHC class I proteins (KIR). Engagement of these receptors inhibits NK cell cytotoxic programs. KIR can be expressed on T cells, and their engagement also results in inhibition of effector functions initiated by the CD3/TCR complex. While human KIR genes belong to the Ig gene superfamily, mouse KIR belong to a family of dimeric lectins. Despite these distinct evolutionary origins, we show here that both HLA-Cw3-specific human p58.183 receptors and H-2D d/k-specific mouse Ly49A receptors recruit the same protein tyrosine phosphatases, PTP1C and PTP1D, upon phosphorylation of critical intracytoplasmic tyrosine residues. These results document a common pathway by which diverse KIR can down- regulate NK and T cell activation programs, and further define the sequence of the immunoreceptor tyrosine-based inhibitory motif (ITIM), initially described in FcgammaRIIB1, and expressed in both human and mouse KIR.
This article has been cited by other articles:
|
|
 |
|
  E. Fourmentraux-Neves, A. Jalil, S. Da Rocha, C. Pichon, S. Chouaib, G. Bismuth, and A. Caignard Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells Blood, September 15, 2008; 112(6): 2381 - 2389. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Estefania, R. Flores, N. Gomez-Lozano, H. Aguilar, M. Lopez-Botet, and C. Vilches Human KIR2DL5 Is an Inhibitory Receptor Expressed on the Surface of NK and T Lymphocyte Subsets J. Immunol., April 1, 2007; 178(7): 4402 - 4410. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Gays, J. G. Aust, D. M. Reid, J. Falconer, N. Toyama-Sorimachi, P. R. Taylor, and C. G. Brooks Ly49B Is Expressed on Multiple Subpopulations of Myeloid Cells J. Immunol., November 1, 2006; 177(9): 5840 - 5851. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Imhof, A.-S. Wavreille, A. May, M. Zacharias, S. Tridandapani, and D. Pei Sequence Specificity of SHP-1 and SHP-2 Src Homology 2 Domains: CRITICAL ROLES OF RESIDUES BEYOND THE pY+3 POSITION J. Biol. Chem., July 21, 2006; 281(29): 20271 - 20282. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Treanor, P. M.P. Lanigan, S. Kumar, C. Dunsby, I. Munro, E. Auksorius, F. J. Culley, M. A. Purbhoo, D. Phillips, M. A.A. Neil, et al. Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses J. Cell Biol., July 3, 2006; 174(1): 153 - 161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Krzewski, X. Chen, J. S. Orange, and J. L. Strominger Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling. J. Cell Biol., April 10, 2006; 173(1): 121 - 132. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Jewett, N. A. Cacalano, C. Head, and A. Teruel Coengagement of CD16 and CD94 receptors mediates secretion of chemokines and induces apoptotic death of naive natural killer cells. Clin. Cancer Res., April 1, 2006; 12(7 Pt 1): 1994 - 2003. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Katz, R. Gazit, T. I. Arnon, T. Gonen-Gross, G. Tarcic, G. Markel, R. Gruda, H. Achdout, O. Drize, S. Merims, et al. MHC Class I-Independent Recognition of NK-Activating Receptor KIR2DS4 J. Immunol., August 1, 2004; 173(3): 1819 - 1825. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-i. Yusa, T. L. Catina, and K. S. Campbell KIR2DL5 Can Inhibit Human NK Cell Activation Via Recruitment of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) J. Immunol., June 15, 2004; 172(12): 7385 - 7392. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Lebbink, T. de Ruiter, A. Verbrugge, W. S. Bril, and L. Meyaard The Mouse Homologue of the Leukocyte-Associated Ig-Like Receptor-1 Is an Inhibitory Receptor That Recruits Src Homology Region 2-Containing Protein Tyrosine Phosphatase (SHP)-2, but Not SHP-1 J. Immunol., May 1, 2004; 172(9): 5535 - 5543. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Toyama-Sorimachi, Y. Tsujimura, M. Maruya, A. Onoda, T. Kubota, S. Koyasu, K. Inaba, and H. Karasuyama Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture PNAS, January 27, 2004; 101(4): 1016 - 1021. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Y. Koh, J. R. Ortaldo, B. R. Blazar, M. Bennett, and W. J. Murphy NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade Blood, December 1, 2003; 102(12): 4067 - 4075. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Inngjerdingen, B. Rolstad, and J. C. Ryan Activating and Inhibitory Ly49 Receptors Modulate NK Cell Chemotaxis to CXC Chemokine Ligand (CXCL) 10 and CXCL12 J. Immunol., September 15, 2003; 171(6): 2889 - 2895. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Ferjoux, F. Lopez, J.-P. Esteve, A. Ferrand, E. Vivier, F. Vely, N. Saint-Laurent, L. Pradayrol, L. Buscail, and C. Susini Critical Role of Src and SHP-2 in sst2 Somatostatin Receptor-mediated Activation of SHP-1 and Inhibition of Cell Proliferation Mol. Biol. Cell, September 1, 2003; 14(9): 3911 - 3928. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Faure, D. F. Barber, S. M. Takahashi, T. Jin, and E. O. Long Spontaneous Clustering and Tyrosine Phosphorylation of NK Cell Inhibitory Receptor Induced by Ligand Binding J. Immunol., June 15, 2003; 170(12): 6107 - 6114. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. H. Westgaard, E. Dissen, K. M. Torgersen, S. Lazetic, L. L. Lanier, J. H. Phillips, and S. Fossum The Lectin-like Receptor KLRE1 Inhibits Natural Killer Cell Cytotoxicity J. Exp. Med., June 2, 2003; 197(11): 1551 - 1561. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-i. Yusa and K. S. Campbell Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) Can Play a Direct Role in the Inhibitory Function of Killer Cell Ig-Like Receptors in Human NK Cells J. Immunol., May 1, 2003; 170(9): 4539 - 4547. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Snyder, M. Lucas, E. Vivier, C. M. Weyand, and J. J. Goronzy Selective Activation of the c-Jun NH2-terminal Protein Kinase Signaling Pathway by Stimulatory KIR in the Absence of KARAP/DAP12 in CD4+ T Cells J. Exp. Med., February 17, 2003; 197(4): 437 - 449. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Cellier, M. Mage, J. Duchene, C. Pecher, R. Couture, J.-L. Bascands, and J.-P. Girolami Bradykinin reduces growth factor-induced glomerular ERK1/2 phosphorylation Am J Physiol Renal Physiol, February 1, 2003; 284(2): F282 - F292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Duchene, J. P. Schanstra, C. Pecher, A. Pizard, C. Susini, J.-P. Esteve, J.-L. Bascands, and J.-P. Girolami A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation J. Biol. Chem., October 18, 2002; 277(43): 40375 - 40383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-i. Yusa, T. L. Catina, and K. S. Campbell SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells J. Immunol., May 15, 2002; 168(10): 5047 - 5057. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Naper, S. Hayashi, G. Lovik, L. Kveberg, E. C. Niemi, B. Rolstad, E. Dissen, J. C. Ryan, and J. T. Vaage Characterization of a Novel Killer Cell Lectin-Like Receptor (KLRH1) Expressed by Alloreactive Rat NK Cells J. Immunol., May 15, 2002; 168(10): 5147 - 5154. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Jiang, B. Zhong, D. L. Gilvary, B. C. Corliss, E. Vivier, E. Hong-Geller, S. Wei, and J. Y. Djeu Syk Regulation of Phosphoinositide 3-Kinase-Dependent NK Cell Function J. Immunol., April 1, 2002; 168(7): 3155 - 3164. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Nakagami, T.-X. Cui, M. Iwai, T. Shiuchi, Y. Takeda-Matsubara, L. Wu, and M. Horiuchi Tumor Necrosis Factor-{alpha} Inhibits Growth Factor-Mediated Cell Proliferation Through SHP-1 Activation in Endothelial Cells Arterioscler. Thromb. Vasc. Biol., February 1, 2002; 22(2): 238 - 242. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Ioannidis, J. Zimmer, F. Beermann, and W. Held Cre Recombinase-Mediated Inactivation of H-2Dd Transgene Expression: Evidence for Partial Missing Self-Recognition by Ly49A NK Cells J. Immunol., December 1, 2001; 167(11): 6256 - 6262. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Seiffert, P. Brossart, C. Cant, M. Cella, M. Colonna, W. Brugger, L. Kanz, A. Ullrich, and H.-J. Buhring Signal-regulatory protein {alpha} (SIRP{alpha}) but not SIRP{beta} is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34+CD38{-} hematopoietic cells Blood, May 1, 2001; 97(9): 2741 - 2749. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. P. Makrigiannis, J. Etzler, R. Winkler-Pickett, A. Mason, J. R. Ortaldo, and S. K. Anderson Identification of the Ly49L protein: evidence for activating counterparts to inhibitory Ly49 proteins J. Leukoc. Biol., November 1, 2000; 68(5): 765 - 771. [Abstract] [Full Text]
|
|
|
|
|
|
B. Lowin-Kropf, B. Kunz, F. Beermann, and W. Held Impaired Natural Killing of MHC Class I-Deficient Targets by NK Cells Expressing a Catalytically Inactive Form of SHP-1 J. Immunol., August 1, 2000; 165(3): 1314 - 1321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Zhao and Z. J. Zhao Dissecting the Interaction of SHP-2 with PZR, an Immunoglobulin Family Protein Containing Immunoreceptor Tyrosine-based Inhibitory Motifs J. Biol. Chem., February 25, 2000; 275(8): 5453 - 5459. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. D. Mousseau, D. Banville, D. L'Abbe, P. Bouchard, and S.-H. Shen PILRalpha , a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILRbeta J. Biol. Chem., February 11, 2000; 275(6): 4467 - 4474. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Nakamura, A. Brauweiler, and J. C. Cambier Effects of Src Homology Domain 2 (SH2)-Containing Inositol Phosphatase (SHIP), SH2-Containing Phosphotyrosine Phosphatase (SHP)-1, and SHP-2 SH2 Decoy Proteins on Fc{gamma}RIIB1-Effector Interactions and Inhibitory Functions J. Immunol., January 15, 2000; 164(2): 631 - 638. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Pauza, K. M. Smith, H. Neal, C. Reilly, L. L. Lanier, and D. Lo Transgenic Expression of Ly-49A in Thymocytes Alters Repertoire Selection J. Immunol., January 15, 2000; 164(2): 884 - 892. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Ortaldo, R. Winkler-Pickett, J. Willette-Brown, R. L. Wange, S. K. Anderson, G. J. Palumbo, L. H. Mason, and D. W. McVicar Structure/Function Relationship of Activating Ly-49D and Inhibitory Ly-49G2 NK Receptors ,2 J. Immunol., November 15, 1999; 163(10): 5269 - 5277. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. P. Makrigiannis, P. Gosselin, L. H. Mason, L. S. Taylor, D. W. McVicar, J. R. Ortaldo, and S. K. Anderson Cloning and Characterization of a Novel Activating Ly49 Closely Related to Ly49A ,2 ,3 J. Immunol., November 1, 1999; 163(9): 4931 - 4938. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ono, T. Yuasa, C. Ra, and T. Takai Stimulatory Function of Paired Immunoglobulin-like Receptor-A in Mast Cell Line by Associating with Subunits Common to Fc Receptors J. Biol. Chem., October 15, 1999; 274(42): 30288 - 30296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y.-J. Jin, C.-L. Yu, and S. J. Burakoff Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity J. Biol. Chem., October 1, 1999; 274(40): 28301 - 28307. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y.-J. Jin, C.-L. Yu, and S. J. Burakoff Human 70-kDa SHP-1L Differs from 68-kDa SHP-1 in Its C-terminal Structure and Catalytic Activity J. Biol. Chem., October 1, 1999; 274(40): 99999 - 99999. [Abstract] [Full Text]
|
|
|
|
|
|
T. C. George, J. R. Ortaldo, S. Lemieux, V. Kumar, and M. Bennett Tolerance and Alloreactivity of the Ly49D Subset of Murine NK Cells J. Immunol., August 15, 1999; 163(4): 1859 - 1867. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. E. M. Bates, N. Fournier, E. Garcia, J. Valladeau, I. Durand, J.-J. Pin, S. M. Zurawski, S. Patel, J. S. Abrams, S. Lebecque, et al. APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif J. Immunol., August 15, 1999; 163(4): 1973 - 1983. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Giezeman-Smits, A. Gorter, R. L. P. van Vlierberghe, J. D. H. v. Eendenburg, A. M. M. Eggermont, G. J. Fleuren, and P. J. K. Kuppen The Regulatory Role of CD45 on Rat NK Cells in Target Cell Lysis J. Immunol., July 1, 1999; 163(1): 71 - 76. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. P. Kung, R.-C. Su, J. Shannon, and R. G. Miller The NKR-P1B Gene Product Is an Inhibitory Receptor on SJL/J NK Cells J. Immunol., May 15, 1999; 162(10): 5876 - 5887. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Carlyle, A. Martin, A. Mehra, L. Attisano, F. W. Tsui, and J. C. Zuniga-Pflucker Mouse NKR-P1B, a Novel NK1.1 Antigen with Inhibitory Function J. Immunol., May 15, 1999; 162(10): 5917 - 5923. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Bernard, A. Cambiaggi, S. Guia, F. Bertucci, S. Granjeaud, R. Tagett, C. N'Guyen, B. R. Jordan, and E. Vivier Engagement of Natural Cytotoxicity Programs Regulates AP-1 Expression in the NKL Human NK Cell Line J. Immunol., April 1, 1999; 162(7): 4062 - 4068. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Schatzle, S. Sheu, S. E. Stepp, P. A. Mathew, M. Bennett, and V. Kumar Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4 PNAS, March 30, 1999; 96(7): 3870 - 3875. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Bruhns, P. Marchetti, W. H. Fridman, E. Vivier, and M. Daeron Differential Roles of N- and C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors J. Immunol., March 15, 1999; 162(6): 3168 - 3175. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Mavoungou, A. Sall, V. Poaty-Mavoungou, F. S. Toure, P. Yaba, A. Delicat, and J. Lansoud-Soukate Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex Clin. Vaccine Immunol., March 1, 1999; 6(2): 254 - 259. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. B. Dustin, D. R. Plas, J. Wong, Y. T. Hu, C. Soto, A. C. Chan, and M. L. Thomas Expression of Dominant-Negative Src-Homology Domain 2-Containing Protein Tyrosine Phosphatase-1 Results in Increased Syk Tyrosine Kinase Activity and B Cell Activation J. Immunol., March 1, 1999; 162(5): 2717 - 2724. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Lu-Kuo, D. M. Joyal, K. F. Austen, and H. R. Katz gp49B1 Inhibits IgE-initiated Mast Cell Activation through Both Immunoreceptor Tyrosine-based Inhibitory Motifs, Recruitment of src Homology 2 Domain-containing Phosphatase-1, and Suppression of Early and Late Calcium Mobilization J. Biol. Chem., February 26, 1999; 274(9): 5791 - 5796. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. C. George, L. H. Mason, J. R. Ortaldo, V. Kumar, and M. Bennett Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells J. Immunol., February 15, 1999; 162(4): 2035 - 2043. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. L. Wang, J. Blasioli, D. R. Plas, M. L. Thomas, and W. M. Yokoyama Specificity of the SH2 Domains of SHP-1 in the Interaction with the Immunoreceptor Tyrosine-Based Inhibitory Motif-Bearing Receptor gp49B J. Immunol., February 1, 1999; 162(3): 1318 - 1323. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. N. Burshtyn, A. S. Lam, M. Weston, N. Gupta, P. A. M. Warmerdam, and E. O. Long Conserved Residues Amino-Terminal of Cytoplasmic Tyrosines Contribute to the SHP-1-Mediated Inhibitory Function of Killer Cell Ig-Like Receptors J. Immunol., January 15, 1999; 162(2): 897 - 902. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Vitale, R. Castriconi, S. Parolini, D. Pende, M.-L. Hsu, L. Moretta, D. Cosman, and A. Moretta The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1+ NK cell clones Int. Immunol., January 1, 1999; 11(1): 29 - 35. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. H. Idris, K. Iizuka, H. R.C. Smith, A. A. Scalzo, and W. M. Yokoyama Genetic Control Of Natural Killing and In Vivo Tumor Elimination by the Chok Locus J. Exp. Med., December 21, 1998; 188(12): 2243 - 2256. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. W. McVicar, L. S. Taylor, P. Gosselin, J. Willette-Brown, A. I. Mikhael, R. L. Geahlen, M. C. Nakamura, P. Linnemeyer, W. E. Seaman, S. K. Anderson, et al. DAP12-mediated Signal Transduction in Natural Killer Cells. A DOMINANT ROLE FOR THE Syk PROTEIN-TYROSINE KINASE J. Biol. Chem., December 4, 1998; 273(49): 32934 - 32942. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. T. Hua, J. R. Gamble, M. A. Vadas, and D. E. Jackson Recruitment and Activation of SHP-1 Protein-tyrosine Phosphatase by Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1). IDENTIFICATION OF IMMUNORECEPTOR TYROSINE-BASED INHIBITORY MOTIF-LIKE BINDING MOTIFS AND SUBSTRATES J. Biol. Chem., October 23, 1998; 273(43): 28332 - 28340. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. A. Binstadt, D. D. Billadeau, B. L. Williams, N. Fang, T. Yi, G. A. Koretzky, R. T. Abraham, and P. J. Leibson SLP-76 Is a Direct Substrate of SHP-1 Recruited to Killer Cell Inhibitory Receptors J. Biol. Chem., October 16, 1998; 273(42): 27518 - 27523. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Marti, C. W. Xu, A. Selvakumar, R. Brent, B. Dupont, and P. D. King LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase PNAS, September 29, 1998; 95(20): 11810 - 11815. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Nakamura and J. C. Cambier B Cell Antigen Receptor (BCR)-Mediated Formation of a SHP-2-pp120 Complex and Its Inhibition by Fe{gamma}RIIB1-BCR Coligation J. Immunol., July 15, 1998; 161(2): 684 - 691. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. F. Timms, K. Carlberg, H. Gu, H. Chen, S. Kamatkar, M. J. S. Nadler, L. R. Rohrschneider, and B. G. Neel Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages Mol. Cell. Biol., July 1, 1998; 18(7): 3838 - 3850. [Abstract] [Full Text]
|
|
|
|
|
|
K. M. Smith, J. Wu, A. B. H. Bakker, J. H. Phillips, and L. L. Lanier Cutting Edge: Ly-49D and Ly-49H Associate with Mouse DAP12 and Form Activating Receptors J. Immunol., July 1, 1998; 161(1): 7 - 10. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Robson MacDonald, R. K. Lees, and W. Held Developmentally Regulated Extinction of Ly-49 Receptor Expression Permits Maturation and Selection of NK1.1+ T Cells J. Exp. Med., Jun |
