| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Immunology, Vol 145, Issue 9 3047-3053, Copyright © 1990 by American Association of Immunologists
ARTICLES |
SR McColl, D Beauseigle, C Gilbert and PH Naccache
Unite de Recherche Inflammation et Immunologie-Rhumatologie, Centre de Recherche du CHUL, Ste-Foy, Quebec, Canada.
Over the last few years, several studies showing that production of superoxide by neutrophils in response to chemotactic factors such as FMLP is enhanced after preincubation of the cells with granulocyte- macrophage (GM)-CSF or TNF-alpha have been published. Subsequent reports have indicated that this effect of the cytokines may be mediated by modulation of the number and/or affinity of surface receptors for FMLP. In the present study we have investigated the effect of preincubation with GM-CSF and TNF-alpha on the oxidative burst induced by sodium fluoride and guanosine 5'-O-(3- thiotriphosphate) (GTP gamma S)-agents which directly activate guanine- nucleotide binding proteins in neutrophils. Pretreatment of neutrophils with either GM-CSF or TNF-alpha dose-dependently enhanced the production of superoxide induced by NaF, as determined by the superoxide dismutase-inhibitable reduction of ferricytochrome c. Furthermore, preincubation of neutrophils with these cytokines enhanced the production of hydrogen peroxide induced by GTP gamma S in electroporated neutrophils. Because both NaF and GTP gamma S directly activate G proteins independently of external receptor-G protein interaction, these results imply that both GM-CSF and TNF-alpha alter the neutrophil signal transduction pathway in response to subsequent agonists independently of a modulation in the expression of the cell surface receptors for such agonists.
This article has been cited by other articles:
|
|
 |
|
  C. Biagioni, F. Favilli, S. Catarzi, T. Marcucci, M. Fazi, F. Tonelli, M. T. Vincenzini, and T. Iantomasi Redox State and O2*- Production in Neutrophils of Crohn's Disease Patients Experimental Biology and Medicine, February 1, 2006; 231(2): 186 - 195. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Guichard, E. Pedruzzi, C. Dewas, M. Fay, C. Pouzet, M. Bens, A. Vandewalle, E. Ogier-Denis, M.-A. Gougerot-Pocidalo, and C. Elbim Interleukin-8-induced Priming of Neutrophil Oxidative Burst Requires Sequential Recruitment of NADPH Oxidase Components into Lipid Rafts J. Biol. Chem., November 4, 2005; 280(44): 37021 - 37032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Elbim, C. Guichard, P. M. C. Dang, M. Fay, E. Pedruzzi, H. Demur, C. Pouzet, J. El Benna, and M.-A. Gougerot-Pocidalo Interleukin-18 Primes the Oxidative Burst of Neutrophils in Response to Formyl-Peptides: Role of Cytochrome b558 Translocation and N-Formyl Peptide Receptor Endocytosis Clin. Vaccine Immunol., March 1, 2005; 12(3): 436 - 446. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Dewas, P. M.-C. Dang, M.-A. Gougerot-Pocidalo, and J. El-Benna TNF-{alpha} Induces Phosphorylation of p47phox in Human Neutrophils: Partial Phosphorylation of p47phox Is a Common Event of Priming of Human Neutrophils by TNF-{alpha} and Granulocyte-Macrophage Colony-Stimulating Factor J. Immunol., October 15, 2003; 171(8): 4392 - 4398. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Brieland, D. Essig, C. Jackson, D. Frank, D. Loebenberg, F. Menzel, B. Arnold, B. DiDomenico, and R. Hare Comparison of Pathogenesis and Host Immune Responses to Candida glabrata and Candida albicans in Systemically Infected Immunocompetent Mice Infect. Immun., August 1, 2001; 69(8): 5046 - 5055. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Takahashi, F. Hato, T. Yamane, H. Fukumasu, K. Suzuki, S. Ogita, Y. Nishizawa, and S. Kitagawa Activation of Human Neutrophil by Cytokine-Activated Endothelial Cells Circ. Res., March 2, 2001; 88(4): 422 - 429. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Koenderman, D. Kanters, B. Maesen, J. Raaijmakers, J.-W. J. Lammers, J. de Kruif, and T. Logtenberg Monitoring of neutrophil priming in whole blood by antibodies isolated from a synthetic phage antibody library J. Leukoc. Biol., July 1, 2000; 68(1): 58 - 64. [Abstract] [Full Text]
|
|
|
|
|
|
P. M.-C. Dang, C. Dewas, M. Gaudry, M. Fay, E. Pedruzzi, M.-A. Gougerot-Pocidalo, and J. El Benna Priming of Human Neutrophil Respiratory Burst by Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF) Involves Partial Phosphorylation of p47phox J. Biol. Chem., July 16, 1999; 274(29): 20704 - 20708. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Meddows-Taylor, D. J. Martin, and C. T. Tiemessen Impaired Interleukin-8-Induced Degranulation of Polymorphonuclear Neutrophils from Human Immunodeficiency Virus Type 1-Infected Individuals Clin. Vaccine Immunol., May 1, 1999; 6(3): 345 - 351. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Roberge, S. R. McColl, B. Larochelle, and J. Gosselin Granulocyte-Macrophage Colony-Stimulating Factor Enhances EBV-Induced Synthesis of Chemotactic Factors in Human Neutrophils J. Immunol., March 1, 1998; 160(5): 2442 - 2448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hachicha, P. Rathanaswami, P. H. Naccache, and S. R. McColl Regulation of Chemokine Gene Expression in Human Peripheral Blood Neutrophils Phagocytosing Microbial Pathogens J. Immunol., January 1, 1998; 160(1): 449 - 454. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. P. Green, A. Chuntharapai, and J. T. Curnutte Interleukin-8 (IL-8), Melanoma Growth-stimulatory Activity, and Neutrophil-activating Peptide Selectively Mediate Priming of the Neutrophil NADPH Oxidase through the Type A or Type B IL-8 Receptor J. Biol. Chem., October 11, 1996; 271(41): 25400 - 25405. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. F. Brizzi, M. G. Aronica, A. Rosso, G. P. Bagnara, Y. Yarden, and L. Pegoraro Granulocyte-Macrophage Colony-stimulating Factor Stimulates JAK2 Signaling Pathway and Rapidly Activates p93[IMAGE], STAT1 p91, and STAT3 p92 in Polymorphonuclear Leukocytes J. Biol. Chem., February 16, 1996; 271(7): 3562 - 3567. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ali, E. D. Tomhave, R. M. Richardson, B. Haribabu, and R. Snyderman Thrombin Primes Responsiveness of Selective Chemoattractant Receptors at a Site Distal to G Protein Activation J. Biol. Chem., February 9, 1996; 271(6): 3200 - 3206. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. A. Ward, M. Nakamura, and K. R. McLeish Priming of the Neutrophil Respiratory Burst Involves p38 Mitogen-activated Protein Kinase-dependent Exocytosis of Flavocytochrome b558-containing Granules J. Biol. Chem., November 17, 2000; 275(47): 36713 - 36719. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
