The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Liew, F. Y.
Right arrow Articles by Millott, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Liew, F. Y.
Right arrow Articles by Millott, S.

The Journal of Immunology, Vol 145, Issue 12 4306-4310, Copyright © 1990 by American Association of Immunologists

ARTICLES

Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide

FY Liew, Y Li and S Millott
Department of Experimental Immunobiology, Wellcome Biotech, Beckenham, Kent, U.K.

CBA mice develop cutaneous lesions when infected with Leishmania major. The disease development was significantly reduced by injecting into the lesion a combination of rIFN-gamma and rTNF-alpha. The doses of IFN- gamma and TNF-alpha used were suboptimal in that either cytokine alone did not have any effect. The therapeutic effect of IFN-gamma and TNF- alpha in vivo is reflected in their ability to activate macrophages to kill the intracellular parasites in vitro. The macrophage leishmanicidal activity induced by TNF-alpha and IFN-gamma can be completely inhibited by a specific inhibitor (L-NG monomethyl arginine) of nitric oxide synthesis. There was a direct correlation between the intracellular killing of the parasites and the production of nitric oxide by the macrophages. In contrast, there was no correlation between leishmanicidal activity and superoxide production by macrophages.


This article has been cited by other articles:


Home page
 Am J Trop Med HygHome page
L. I. A. Pereira, M. L. Dorta, A. J. C. S. Pereira, R. P. Bastos, M. A. P. Oliveira, S. A. Pinto, H. Galdino Jr, W. Mayrink, W. Barcelos, V. P. C. P. Toledo, et al.
Increase of NK Cells and Proinflammatory Monocytes Are Associated with the Clinical Improvement of Diffuse Cutaneous Leishmaniasis after Immunochemotherapy with BCG/Leishmania Antigens
Am J Trop Med Hyg, September 1, 2009; 81(3): 378 - 383.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Samant, R. Gupta, S. Kumari, P. Misra, P. Khare, P. K. Kushawaha, A. A. Sahasrabuddhe, and A. Dube
Immunization with the DNA-Encoding N-Terminal Domain of Proteophosphoglycan of Leishmania donovani Generates Th1-Type Immunoprotective Response against Experimental Visceral Leishmaniasis
J. Immunol., July 1, 2009; 183(1): 470 - 479.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
S. Banerjee, J. Ghosh, S. Sen, R. Guha, R. Dhar, M. Ghosh, S. Datta, B. Raychaudhury, K. Naskar, A. K. Haldar, et al.
Designing Therapies against Experimental Visceral Leishmaniasis by Modulating the Membrane Fluidity of Antigen-Presenting Cells
Infect. Immun., June 1, 2009; 77(6): 2330 - 2342.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Mise-Omata, E. Kuroda, T. Sugiura, U. Yamashita, Y. Obata, and T. S. Doi
The NF-{kappa}B RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation
J. Immunol., April 15, 2009; 182(8): 4910 - 4916.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
K. S. Charret, R. F. Rodrigues, A. M. R. Bernardino, A. O. Gomes, A. V. Carvalho, M. M. Canto-Cavalheiro, L. Leon, and V. F. Amaral
Effect of Oral Treatment with Pyrazole Carbohydrazide Derivatives against Murine Infection by Leishmania amazonensis
Am J Trop Med Hyg, April 1, 2009; 80(4): 568 - 573.
[Abstract] [Full Text] [PDF]

Home page
 Antimicrob. Agents Chemother.Home page
R. F. Rodrigues, K. S. Charret, E. F. da Silva, A. Echevarria, V. F. Amaral, L. L. Leon, and M. M. Canto-Cavalheiro
Antileishmanial Activity of 1,3,4-Thiadiazolium-2-Aminide in Mice Infected with Leishmania amazonensis
Antimicrob. Agents Chemother., February 1, 2009; 53(2): 839 - 842.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
A. M. Gasparri, E. Jachetti, B. Colombo, A. Sacchi, F. Curnis, G.-P. Rizzardi, C. Traversari, M. Bellone, and A. Corti
Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFN{gamma}
Mol. Cancer Ther., December 1, 2008; 7(12): 3859 - 3866.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. C. Cowley, J. D. Sedgwick, and K. L. Elkins
Differential Requirements by CD4+ and CD8+ T Cells for Soluble and Membrane TNF in Control of Francisella tularensis Live Vaccine Strain Intramacrophage Growth
J. Immunol., December 1, 2007; 179(11): 7709 - 7719.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
G. Xu, D. Liu, Y. Fan, X. Yang, H. Korner, Y.-X. Fu, and J. E. Uzonna
Lymphotoxin {alpha}beta2 (Membrane Lymphotoxin) Is Critically Important for Resistance to Leishmania major Infection in Mice
J. Immunol., October 15, 2007; 179(8): 5358 - 5366.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. Silvestre, A. Cordeiro-Da-Silva, N. Santarem, B. Vergnes, D. Sereno, and A. Ouaissi
SIR2-Deficient Leishmania infantum Induces a Defined IFN-{gamma}/IL-10 Pattern That Correlates with Protection
J. Immunol., September 1, 2007; 179(5): 3161 - 3170.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
E. Torrado, S. Adusumilli, A. G. Fraga, P. L. C. Small, A. G. Castro, and J. Pedrosa
Mycolactone-Mediated Inhibition of Tumor Necrosis Factor Production by Macrophages Infected with Mycobacterium ulcerans Has Implications for the Control of Infection
Infect. Immun., August 1, 2007; 75(8): 3979 - 3988.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. R. Faria, K. J. Gollob, J. Barbosa Jr, A. Schriefer, P. R. L. Machado, H. Lessa, L. P. Carvalho, M. A. Romano-Silva, A. R. de Jesus, E. M. Carvalho, et al.
Decreased In Situ Expression of Interleukin-10 Receptor Is Correlated with the Exacerbated Inflammatory and Cytotoxic Responses Observed in Mucosal Leishmaniasis
Infect. Immun., December 1, 2005; 73(12): 7853 - 7859.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. Basu, S. Bhaumik, J. M. Basu, K. Naskar, T. De, and S. Roy
Kinetoplastid Membrane Protein-11 DNA Vaccination Induces Complete Protection against Both Pentavalent Antimonial-Sensitive and -Resistant Strains of Leishmania donovani That Correlates with Inducible Nitric Oxide Synthase Activity and IL-4 Generation: Evidence for Mixed Th1- and Th2-Like Responses in Visceral Leishmaniasis
J. Immunol., June 1, 2005; 174(11): 7160 - 7171.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
F. Curnis, A. Gasparri, A. Sacchi, A. Cattaneo, F. Magni, and A. Corti
Targeted Delivery of IFN{gamma} to Tumor Vessels Uncouples Antitumor from Counterregulatory Mechanisms
Cancer Res., April 1, 2005; 65(7): 2906 - 2913.
[Abstract] [Full Text] [PDF]

Home page
 Vet PatholHome page
C. Brachelente, N. Muller, M. G. Doherr, U. Sattler, and M. Welle
Cutaneous Leishmaniasis in Naturally Infected Dogs is Associated with a T Helper-2-biased Immune Response
Vet. Pathol., February 1, 2005; 42(2): 166 - 175.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. J. Costa, C. Favali, J. Clarencio, L. Afonso, V. Conceicao, J. C. Miranda, R. G. Titus, J. Valenzuela, M. Barral-Netto, A. Barral, et al.
Lutzomyia longipalpis Salivary Gland Homogenate Impairs Cytokine Production and Costimulatory Molecule Expression on Human Monocytes and Dendritic Cells
Infect. Immun., March 1, 2004; 72(3): 1298 - 1305.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
H. Qi, J. Ji, N. Wanasen, and L. Soong
Enhanced Replication of Leishmania amazonensis Amastigotes in Gamma Interferon-Stimulated Murine Macrophages: Implications for the Pathogenesis of Cutaneous Leishmaniasis
Infect. Immun., February 1, 2004; 72(2): 988 - 995.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
E. Roth and H. Pircher
IFN-{gamma} Promotes Fas Ligand- and Perforin-Mediated Liver Cell Destruction by Cytotoxic CD8 T Cells
J. Immunol., February 1, 2004; 172(3): 1588 - 1594.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
K. R. Morris, R. D. Lutz, H.-S. Choi, T. Kamitani, K. Chmura, and E. D. Chan
Role of the NF-{kappa}B Signaling Pathway and {kappa}B cis-Regulatory Elements on the IRF-1 and iNOS Promoter Regions in Mycobacterial Lipoarabinomannan Induction of Nitric Oxide
Infect. Immun., March 1, 2003; 71(3): 1442 - 1452.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
D. Artis, K. Speirs, K. Joyce, M. Goldschmidt, J. Caamano, C. A. Hunter, and P. Scott
NF-{kappa}B1 Is Required for Optimal CD4+ Th1 Cell Development and Resistance to Leishmania major
J. Immunol., February 15, 2003; 170(4): 1995 - 2003.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
O. Bacellar, H. Lessa, A. Schriefer, P. Machado, A. Ribeiro de Jesus, W. O. Dutra, K. J. Gollob, and E. M. Carvalho
Up-Regulation of Th1-Type Responses in Mucosal Leishmaniasis Patients
Infect. Immun., December 1, 2002; 70(12): 6734 - 6740.
[Abstract] [Full Text] [PDF]

Home page
 CVIHome page
L. Villamil, C. Tafalla, A. Figueras, and B. Novoa
Evaluation of Immunomodulatory Effects of Lactic Acid Bacteria in Turbot (Scophthalmus maximus)
Clin. Vaccine Immunol., November 1, 2002; 9(6): 1318 - 1323.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. D. Lehner, F. Schwoebel, A. Kotlyarov, M. Leist, M. Gaestel, and T. Hartung
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2-Deficient Mice Show Increased Susceptibility to Listeria monocytogenes Infection
J. Immunol., May 1, 2002; 168(9): 4667 - 4673.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. J. Greenwald, A. J. McAdam, D. Van der Woude, A. R. Satoskar, and A. H. Sharpe
Cutting Edge: Inducible Costimulator Protein Regulates Both Th1 and Th2 Responses to Cutaneous Leishmaniasis
J. Immunol., February 1, 2002; 168(3): 991 - 995.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Saio, S. Radoja, M. Marino, and A. B. Frey
Tumor-Infiltrating Macrophages Induce Apoptosis in Activated CD8+ T Cells by a Mechanism Requiring Cell Contact and Mediated by Both the Cell-Associated Form of TNF and Nitric Oxide
J. Immunol., November 15, 2001; 167(10): 5583 - 5593.
[Abstract] [Full Text] [PDF]

Home page
 Ann Rheum DisHome page
S Stenger and M Rollinghoff
Role of cytokines in the innate immune response to intracellular pathogens
Ann Rheum Dis, November 1, 2001; 60(90003): iii43 - 46.
[Full Text] [PDF]

Home page
 J. Immunol.Home page
K. R. Gantt, T. L. Goldman, M. L. McCormick, M. A. Miller, S. M. B. Jeronimo, E. T. Nascimento, B. E. Britigan, and M. E. Wilson
Oxidative Responses of Human and Murine Macrophages During Phagocytosis of Leishmania chagasi
J. Immunol., July 15, 2001; 167(2): 893 - 901.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
E. S. Chen, B. M. Greenlee, M. Wills-Karp, and D. R. Moller
Attenuation of Lung Inflammation and Fibrosis in Interferon-{gamma}-Deficient Mice after Intratracheal Bleomycin
Am. J. Respir. Cell Mol. Biol., May 1, 2001; 24(5): 545 - 555.
[Abstract] [Full Text]

Home page
 Clin. Microbiol. Rev.Home page
E. Handman
Leishmaniasis: Current Status of Vaccine Development
Clin. Microbiol. Rev., April 1, 2001; 14(2): 229 - 243.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
E. D. Chan, K. R. Morris, J. T. Belisle, P. Hill, L. K. Remigio, P. J. Brennan, and D. W. H. Riches
Induction of Inducible Nitric Oxide Synthase-NO{middle dot} by Lipoarabinomannan of Mycobacterium tuberculosis Is Mediated by MEK1-ERK, MKK7-JNK, and NF-{kappa}B Signaling Pathways
Infect. Immun., April 1, 2001; 69(4): 2001 - 2010.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
P. Wilhelm, U. Ritter, S. Labbow, N. Donhauser, M. Rollinghoff, C. Bogdan, and H. Korner
Rapidly Fatal Leishmaniasis in Resistant C57BL/6 Mice Lacking TNF
J. Immunol., March 15, 2001; 166(6): 4012 - 4019.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. Das, N. Datta, S. Bandyopadhyay, and P. K. Das
Successful Therapy of Lethal Murine Visceral Leishmaniasis with Cystatin Involves Up-Regulation of Nitric Oxide and a Favorable T Cell Response
J. Immunol., March 15, 2001; 166(6): 4020 - 4028.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
P. C. Melby, B. Chandrasekar, W. Zhao, and J. E. Coe
The Hamster as a Model of Human Visceral Leishmaniasis: Progressive Disease and Impaired Generation of Nitric Oxide in the Face of a Prominent Th1-Like Cytokine Response
J. Immunol., February 1, 2001; 166(3): 1912 - 1920.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
A. Nansen and A. Randrup Thomsen
Viral Infection Causes Rapid Sensitization to Lipopolysaccharide: Central Role of IFN-{{alpha}}{{beta}}
J. Immunol., January 15, 2001; 166(2): 982 - 988.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
H. W. Murray, A. Jungbluth, E. Ritter, C. Montelibano, and M. W. Marino
Visceral Leishmaniasis in Mice Devoid of Tumor Necrosis Factor and Response to Treatment
Infect. Immun., November 1, 2000; 68(11): 6289 - 6293.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. V. C. Lonardoni, M. Russo, and S. Jancar
Essential Role of Platelet-Activating Factor in Control of Leishmania (Leishmania) amazonensis Infection
Infect. Immun., November 1, 2000; 68(11): 6355 - 6361.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
D. Imanishi, K. Yamamoto, H. Tsushima, Y. Miyazaki, K. Kuriyama, M. Tomonaga, and T. Matsuyama
Identification of a Novel Cytokine Response Element in the Human IFN Regulatory Factor-1 Gene Promoter
J. Immunol., October 1, 2000; 165(7): 3907 - 3916.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
K. Ohkusu, T. Yoshimoto, K. Takeda, T. Ogura, S.-i. Kashiwamura, Y. Iwakura, S. Akira, H. Okamura, and K. Nakanishi
Potentiality of Interleukin-18 as a Useful Reagent for Treatment and Prevention of Leishmania major Infection
Infect. Immun., May 1, 2000; 68(5): 2449 - 2456.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Nashleanas and P. Scott
Activated T Cells Induce Macrophages To Produce NO and Control Leishmania major in the Absence of Tumor Necrosis Factor Receptor p55
Infect. Immun., March 1, 2000; 68(3): 1428 - 1434.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. Wolday, H. Akuffo, A. Demissie, and S. Britton
Role of Leishmania donovani and Its Lipophosphoglycan in CD4+ T-cell Activation-Induced Human Immunodeficiency Virus Replication
Infect. Immun., October 1, 1999; 67(10): 5258 - 5264.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
H. Sam, Z. Su, and M. M. Stevenson
Deficiency in Tumor Necrosis Factor Alpha Activity Does Not Impair Early Protective Th1 Responses against Blood-Stage Malaria
Infect. Immun., May 1, 1999; 67(5): 2660 - 2664.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
A. S. MacFarlane, M. G. Schwacha, and T. K. Eisenstein
In Vivo Blockage of Nitric Oxide with Aminoguanidine Inhibits Immunosuppression Induced by an Attenuated Strain of Salmonella typhimurium, Potentiates Salmonella Infection, and Inhibits Macrophage and Polymorphonuclear Leukocyte Influx into the Spleen
Infect. Immun., February 1, 1999; 67(2): 891 - 898.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. Li, C. A. Hunter, and J. P. Farrell
Anti-TGF-{beta} Treatment Promotes Rapid Healing of Leishmania major Infection in Mice by Enhancing In Vivo Nitric Oxide Production
J. Immunol., January 15, 1999; 162(2): 974 - 979.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
J Alexander, A. Satoskar, and D. Russell
Leishmania species: models of intracellular parasitism
J. Cell Sci., January 9, 1999; 112(18): 2993 - 3002.
[Abstract] [PDF]

Home page
 J. Immunol.Home page
E. D. Chan, B. W. Winston, S.-T. Uh, M. W. Wynes, D. M. Rose, and D. W. H. Riches
Evaluation of the Role of Mitogen-Activated Protein Kinases in the Expression of Inducible Nitric Oxide Synthase by IFN-{gamma} and TNF-{alpha} in Mouse Macrophages
J. Immunol., January 1, 1999; 162(1): 415 - 422.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
K. Hung, R. Hayashi, A. Lafond-Walker, C. Lowenstein, D. Pardoll, and H. Levitsky
The Central Role of CD4+ T Cells in the Antitumor Immune Response
J. Exp. Med., December 21, 1998; 188(12): 2357 - 2368.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. M. Stamm, A. Raisanen-Sokolowski, M. Okano, M. E. Russell, J. R. David, and A. R. Satoskar
Mice with STAT6-Targeted Gene Disruption Develop a Th1 Response and Control Cutaneous Leishmaniasis
J. Immunol., December 1, 1998; 161(11): 6180 - 6188.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
P. A. Mackowiak
Concepts of Fever
Arch Intern Med, September 28, 1998; 158(17): 1870 - 1881.
[Abstract] [Full Text]

Home page
 J. Immunol.Home page
J. D. Gorham, M. L. Guler, D. Fenoglio, U. Gubler, and K. M. Murphy
Low Dose TGF-{beta} Attenuates IL-12 Responsiveness in Murine Th Cells
J. Immunol., August 15, 1998; 161(4): 1664 - 1670.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. Allendoerfer and G. S. Deepe Jr.
Blockade of Endogenous TNF-{alpha} Exacerbates Primary and Secondary Pulmonary Histoplasmosis by Differential Mechanisms
J. Immunol., June 15, 1998; 160(12): 6072 - 6082.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Nashleanas, S. Kanaly, and P. Scott
Control of Leishmania major Infection in Mice Lacking TNF Receptors
J. Immunol., June 1, 1998; 160(11): 5506 - 5513.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
A. Gross, S. Spiesser, A. Terraza, B. Rouot, E. Caron, and J. Dornand
Expression and Bactericidal Activity of Nitric Oxide Synthase in Brucella suis-Infected Murine Macrophages
Infect. Immun., April 1, 1998; 66(4): 1309 - 1316.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
D. Xu, S. J. McSorley, L. Tetley, S. Chatfield, G. Dougan, W. L. Chan, A. Satoskar, J. R. David, and F. Y. Liew
Protective Effect on Leishmania major Infection of Migration Inhibitory Factor, TNF-{alpha}, and IFN-{gamma} Administered Orally via Attenuated Salmonella typhimurium
J. Immunol., February 1, 1998; 160(3): 1285 - 1289.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. A. Taylor, R. Stauber, S. Rulong, E. Hudson, V. Pei, G. N. Pavlakis, J. H. Resau, and G. F. Vande Woude
The Inducibly Expressed GTPase Localizes to the Endoplasmic Reticulum, Independently of GTP Binding
J. Biol. Chem., April 18, 1997; 272(16): 10639 - 10645.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
T. M. Scharton-Kersten, G. Yap, J. Magram, and A. Sher
Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen Toxoplasma gondii
J. Exp. Med., April 7, 1997; 185(7): 1261 - 1274.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. A. Taylor, M. Jeffers, D. A. Largaespada, N. A. Jenkins, N. G. Copeland, and G. F.V. Woude
Identification of a Novel GTPase, the Inducibly Expressed GTPase, That Accumulates in Response to Interferon gamma
J. Biol. Chem., August 23, 1996; 271(34): 20399 - 20405.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
C. Szabo, B. Zingarelli, and A. L. Salzman
Role of Poly-ADP Ribosyltransferase Activation in the Vascular Contractile and Energetic Failure Elicited by Exogenous and Endogenous Nitric Oxide and Peroxynitrite
Circ. Res., June 1, 1996; 78(6): 1051 - 1063.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
K. Mossman, C. Upton, and G. McFadden
The Myxoma Virus-soluble Interferon-[IMAGE] Receptor Homolog, M-T7, Inhibits Interferon-[IMAGE] in a Species-specific Manner
J. Biol. Chem., February 17, 1995; 270(7): 3031 - 3038.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Vazquez-Torres, G. Fantuzzi, C. K. Edwards III, C. A. Dinarello, and F. C. Fang
Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages
PNAS, February 27, 2001; 98(5): 2561 - 2565.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1990 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1990 by The American Association of Immunologists, Inc. All rights reserved.