The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Banerjee, S.
Right arrow Articles by David, C. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Banerjee, S.
Right arrow Articles by David, C. S.

The Journal of Immunology, Vol 141, Issue 4 1150-1154, Copyright © 1988 by American Association of Immunologists

ARTICLES

Immunosuppression of collagen-induced arthritis in mice with an anti-IL- 2 receptor antibody

S Banerjee, BY Wei, K Hillman, HS Luthra and CS David
Department of Immunology and Rheumatology, Mayo Clinic, Rochester, MN 55905.

The use of an anti-IL-2R antibody, 7D4, was investigated in vivo in the suppression of collagen-induced arthritis in mice. 7D4 was shown to reduce the incidence of arthritis in a group of mice immunized with type II collagen as compared with a group similarly immunized with collagen and treated with a control isotype matched anti-Forsmann antibody. 7D4 was also shown to reduce the severity of arthritis in the treated mice as compared to the mice in the group treated with the control antibody. Anti-IL-2R antibodies may be useful in the treatment of autoimmune diseases by selectively suppressing activated T cells.


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
P Mukherjee, B Wu, L Mayton, S-H Kim, P D Robbins, and P H Wooley
TNF receptor gene therapy results in suppression of IgG2a anticollagen antibody in collagen induced arthritis
Ann Rheum Dis, August 1, 2003; 62(8): 707 - 714.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
S. B. Han, S. H. Park, Y. J. Jeon, Y. K. Kim, H. M. Kim, and K. H. Yang
Prodigiosin Blocks T Cell Activation by Inhibiting Interleukin-2Ralpha Expression and Delays Progression of Autoimmune Diabetes and Collagen-Induced Arthritis
J. Pharmacol. Exp. Ther., November 1, 2001; 299(2): 415 - 425.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Thornton, G. P. Boivin, K. N. Kim, F. D. Finkelman, and R. Hirsch
Heterogeneous Effects of IL-2 on Collagen-Induced Arthritis
J. Immunol., August 1, 2000; 165(3): 1557 - 1563.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. Seetharaman, A. L. Mora, G. Nabozny, M. Boothby, and J. Chen
Essential Role of T Cell NF-{kappa}B Activation in Collagen-Induced Arthritis
J. Immunol., August 1, 1999; 163(3): 1577 - 1583.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
A. Corthay, A. Johansson, M. Vestberg, and R. Holmdahl
Collagen-induced arthritis development requires {alpha}{beta} T cells but not {gamma}{delta} T cells: studies with T cell-deficient (TCR mutant) mice
Int. Immunol., July 1, 1999; 11(7): 1065 - 1073.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1988 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1988 by The American Association of Immunologists, Inc. All rights reserved.