The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mosmann, T. R.
Right arrow Articles by Coffman, R. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mosmann, T. R.
Right arrow Articles by Coffman, R. L.
Right arrowPubmed/NCBI databases
*Substance via MeSH

The Journal of Immunology, Vol 136, Issue 7 2348-2357, Copyright © 1986 by American Association of Immunologists

ARTICLES

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

TR Mosmann, H Cherwinski, MW Bond, MA Giedlin and RL Coffman

A panel of antigen-specific mouse helper T cell clones was characterized according to patterns of lymphokine activity production, and two types of T cell were distinguished. Type 1 T helper cells (TH1) produced IL 2, interferon-gamma, GM-CSF, and IL 3 in response to antigen + presenting cells or to Con A, whereas type 2 helper T cells (TH2) produced IL 3, BSF1, and two other activities unique to the TH2 subset, a mast cell growth factor distinct from IL 3 and a T cell growth factor distinct from IL 2. Clones representing each type of T cell were characterized, and the pattern of lymphokine activities was consistent within each set. The secreted proteins induced by Con A were analyzed by biosynthetic labeling and SDS gel electrophoresis, and significant differences were seen between the two groups of T cell line. Both types of T cell grew in response to alternating cycles of antigen stimulation, followed by growth in IL 2-containing medium. Examples of both types of T cell were also specific for or restricted by the I region of the MHC, and the surface marker phenotype of the majority of both types was Ly-1+, Lyt-2-, L3T4+, Both types of helper T cell could provide help for B cells, but the nature of the help differed. TH1 cells were found among examples of T cell clones specific for chicken RBC and mouse alloantigens. TH2 cells were found among clones specific for mouse alloantigens, fowl gamma-globulin, and KLH. The relationship between these two types of T cells and previously described subsets of T helper cells is discussed.


This article has been cited by other articles:


Home page
 Am. J. Pathol.Home page
K. T. Montone
Regulating the T-Cell Immune Response Toward the H99 Strain of Cryptococcus neoformans
Am. J. Pathol., December 1, 2009; 175(6): 2255 - 2256.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
T. Juelich, E. Sutcliffe, A. Denton, Y. He, P. C. Doherty, C. Parish, S. J. Turner, D. Tremethick, and S. Rao
Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression
J. Immunol., December 1, 2009; 183(11): 7063 - 7072.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. H. Lee, C. Wang, and C. H. Kim
FoxP3+ Regulatory T Cells Restrain Splenic Extramedullary Myelopoiesis via Suppression of Hemopoietic Cytokine-Producing T Cells
J. Immunol., November 15, 2009; 183(10): 6377 - 6386.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Y.-S. Kim, S.-W. Hong, J.-P. Choi, T.-S. Shin, H.-G. Moon, E.-J. Choi, S. G. Jeon, S.-Y. Oh, Y. S. Gho, Z. Zhu, et al.
Vascular Endothelial Growth Factor Is a Key Mediator in the Development of T Cell Priming and Its Polarization to Type 1 and Type 17 T Helper Cells in the Airways
J. Immunol., October 15, 2009; 183(8): 5113 - 5120.
[Abstract] [Full Text] [PDF]

Home page
 J Mol Cell BiolHome page
Y. Y. Wan and R. A. Flavell
How Diverse--CD4 Effector T Cells and their Functions
J Mol Cell Biol, October 1, 2009; 1(1): 20 - 36.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
F. Annunziato and S. Romagnani
Do studies in humans better depict Th17 cells?
Blood, September 10, 2009; 114(11): 2213 - 2219.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
J. H. T. Bates, M. Rincon, and C. G. Irvin
Animal models of asthma
Am J Physiol Lung Cell Mol Physiol, September 1, 2009; 297(3): L401 - L410.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
R. M. Locksley
Nine lives: plasticity among T helper cell subsets
J. Exp. Med., August 3, 2009; 206(8): 1643 - 1646.
[Abstract] [Full Text] [PDF]

Home page
 Mult SclerHome page
R Pedotti, M Farinotti, C Falcone, L Borgonovo, P Confalonieri, A Campanella, R Mantegazza, E Pastorello, and G Filippini
Allergy and multiple sclerosis: a population-based case-control study
Multiple Sclerosis, August 1, 2009; 15(8): 899 - 906.
[Abstract] [PDF]

Home page
 GutHome page
S Brand
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
Gut, August 1, 2009; 58(8): 1152 - 1167.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
S. Kim, J. Y. Yang, K. Lee, K. H. Oh, M. Gi, J. M. Kim, D. J. Paik, S. Hong, and J. Youn
Bacillus subtilis-specific poly-{gamma}-glutamic acid regulates development pathways of naive CD4+ T cells through antigen-presenting cell-dependent and -independent mechanisms
Int. Immunol., August 1, 2009; 21(8): 977 - 990.
[Abstract] [Full Text] [PDF]

Home page
 Evid Based Complement Alternat MedHome page
A. Vojdani and J. Lambert
The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I
Evid. Based Complement. Altern. Med., July 21, 2009; (2009) nep062v1.
[Abstract] [Full Text] [PDF]

Home page
 Therapeutic Advances in Neurological DisordersHome page
C. L. Helliwell and A. J. Coles
Monoclonal antibodies in multiple sclerosis treatment: current and future steps
Therapeutic Advances in Neurological Disorders, July 1, 2009; 2(4): 195 - 203.
[PDF]

Home page
 Int ImmunolHome page
K. Nakano, T. Higashi, R. Takagi, K. Hashimoto, Y. Tanaka, and S. Matsushita
Dopamine released by dendritic cells polarizes Th2 differentiation
Int. Immunol., June 1, 2009; 21(6): 645 - 654.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
J. V. Fahy
Eosinophilic and Neutrophilic Inflammation in Asthma: Insights from Clinical Studies
Proceedings of the ATS, May 1, 2009; 6(3): 256 - 259.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
C. Bergeron, W. Al-Ramli, and Q. Hamid
Remodeling in Asthma
Proceedings of the ATS, May 1, 2009; 6(3): 301 - 305.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
A. Awasthi and V. K. Kuchroo
Th17 cells: from precursors to players in inflammation and infection
Int. Immunol., May 1, 2009; 21(5): 489 - 498.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
U. Maitra, S. Davis, C. M. Reilly, and L. Li
Differential Regulation of Foxp3 and IL-17 Expression in CD4 T Helper Cells by IRAK-1
J. Immunol., May 1, 2009; 182(9): 5763 - 5769.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Soc. Nephrol.Home page
H.-J. Paust, J.-E. Turner, O. M. Steinmetz, A. Peters, F. Heymann, C. Holscher, G. Wolf, C. Kurts, H.-W. Mittrucker, R. A.K. Stahl, et al.
The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis
J. Am. Soc. Nephrol., May 1, 2009; 20(5): 969 - 979.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Soc. Nephrol.Home page
S. Hamour and A. D. Salama
17 and 23: Prime Numbers that Matter
J. Am. Soc. Nephrol., May 1, 2009; 20(5): 925 - 927.
[Full Text] [PDF]

Home page
 Clin. Microbiol. Rev.Home page
T. H. Mogensen
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
Clin. Microbiol. Rev., April 1, 2009; 22(2): 240 - 273.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. Galli, D. Medini, E. Borgogni, L. Zedda, M. Bardelli, C. Malzone, S. Nuti, S. Tavarini, C. Sammicheli, A. K. Hilbert, et al.
From the Cover: Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels
PNAS, March 10, 2009; 106(10): 3877 - 3882.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
B. Liu, A. M. Woltman, H. L. A. Janssen, and A. Boonstra
Modulation of dendritic cell function by persistent viruses
J. Leukoc. Biol., February 1, 2009; 85(2): 205 - 214.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
J.-J. Filen, S. Filen, R. Moulder, S. Tuomela, H. Ahlfors, A. West, P. Kouvonen, S. Kantola, M. Bjorkman, M. Katajamaa, et al.
Quantitative Proteomics Reveals GIMAP Family Proteins 1 and 4 to Be Differentially Regulated during Human T Helper Cell Differentiation
Mol. Cell. Proteomics, January 1, 2009; 8(1): 32 - 44.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
N. M. Heller, X. Qi, I. S. Junttila, K. A. Shirey, S. N. Vogel, W. E. Paul, and A. D. Keegan
Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
Sci. Signal., December 23, 2008; 1(51): ra17 - ra17.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
A. M. Davis, H. J. Ramos, L. S. Davis, and J. D. Farrar
Cutting Edge: A T-bet-Independent Role for IFN-{alpha}/{beta} in Regulating IL-2 Secretion in Human CD4+ Central Memory T Cells
J. Immunol., December 15, 2008; 181(12): 8204 - 8208.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Epidemiol. Biomarkers Prev.Home page
H.-L. Wong, R. M. Pfeiffer, T. R. Fears, R. Vermeulen, S. Ji, and C. S. Rabkin
Reproducibility and Correlations of Multiplex Cytokine Levels in Asymptomatic Persons
Cancer Epidemiol. Biomarkers Prev., December 1, 2008; 17(12): 3450 - 3456.
[Abstract] [Full Text] [PDF]

Home page
 GutHome page
T Kobayashi, S Okamoto, T Hisamatsu, N Kamada, H Chinen, R Saito, M T Kitazume, A Nakazawa, A Sugita, K Koganei, et al.
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
Gut, December 1, 2008; 57(12): 1682 - 1689.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
F. Meiler, J. Zumkehr, S. Klunker, B. Ruckert, C. A. Akdis, and M. Akdis
In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
J. Exp. Med., November 24, 2008; 205(12): 2887 - 2898.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
F. Annunziato, L. Cosmi, F. Liotta, E. Maggi, and S. Romagnani
The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation
Int. Immunol., November 1, 2008; 20(11): 1361 - 1368.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. Wang, N. van Panhuys, J. Hu-Li, S. Kim, G. Le Gros, and B. Min
Blimp-1 Induced by IL-4 Plays a Critical Role in Suppressing IL-2 Production in Activated CD4 T Cells
J. Immunol., October 15, 2008; 181(8): 5249 - 5256.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
W. E. Paul
Th1 Fate Determination in CD4+ T Cells: Notice Is Served of the Importance of IL-12!
J. Immunol., October 1, 2008; 181(7): 4435 - 4436.
[Full Text] [PDF]

Home page
 FASEB J.Home page
B. Csoka, L. Himer, Z. Selmeczy, E. S. Vizi, P. Pacher, C. Ledent, E. A. Deitch, Z. Spolarics, Z. H. Nemeth, and G. Hasko
Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function
FASEB J, October 1, 2008; 22(10): 3491 - 3499.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
H.-J. van den Ham and R. J. de Boer
From the two-dimensional Th1 and Th2 phenotypes to high-dimensional models for gene regulation
Int. Immunol., October 1, 2008; 20(10): 1269 - 1277.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
J. M. Brenchley, M. Paiardini, K. S. Knox, A. I. Asher, B. Cervasi, T. E. Asher, P. Scheinberg, D. A. Price, C. A. Hage, L. M. Kholi, et al.
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
Blood, October 1, 2008; 112(7): 2826 - 2835.
[Abstract] [Full Text] [PDF]

Home page
 Journal of the American Animal Hospital AssociationHome page
S. Tzannes, P. Ibarrola, D. J. Batchelor, R. D. Burrow, and L. Blackwood
Use of Recombinant Human Interferon Alpha-2a in the Management of a Dog With Epitheliotropic Lymphoma
J. Am. Anim. Hosp. Assoc., September 1, 2008; 44(5): 276 - 282.
[Abstract] [Full Text] [PDF]

Home page
 JDRHome page
S.L. Gaffen and G. Hajishengallis
A New Inflammatory Cytokine on the Block: Re-thinking Periodontal Disease and the Th1/Th2 Paradigm in the Context of Th17 Cells and IL-17
Journal of Dental Research, September 1, 2008; 87(9): 817 - 828.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. A. Brown
IL-4 Production by T Cells: You Need a Little to Get a Lot
J. Immunol., September 1, 2008; 181(5): 2941 - 2942.
[Full Text] [PDF]

Home page
 BloodHome page
J. Zhu and W. E. Paul
CD4 T cells: fates, functions, and faults
Blood, September 1, 2008; 112(5): 1557 - 1569.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
P. Muranski, A. Boni, P. A. Antony, L. Cassard, K. R. Irvine, A. Kaiser, C. M. Paulos, D. C. Palmer, C. E. Touloukian, K. Ptak, et al.
Tumor-specific Th17-polarized cells eradicate large established melanoma
Blood, July 15, 2008; 112(2): 362 - 373.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Bouguermouh, V. Q. Van, J. Martel, P. Gautier, M. Rubio, and M. Sarfati
CD47 Expression on T Cell Is a Self-Control Negative Regulator of Type 1 Immune Response
J. Immunol., June 15, 2008; 180(12): 8073 - 8082.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Okutsu, Y. Yoshida, X. Zhang, A. Tamagawa, T. Ohkubo, I. Tsuji, and R. Nagatomi
Exercise training enhances in vivo tuberculosis purified protein derivative response in the elderly
J Appl Physiol, June 1, 2008; 104(6): 1690 - 1696.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
B. Li, M. VanRoey, F. Triebel, and K. Jooss
Lymphocyte Activation Gene-3 Fusion Protein Increases the Potency of a Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Cell Immunotherapy
Clin. Cancer Res., June 1, 2008; 14(11): 3545 - 3554.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
M. Yamashita, M. Kuwahara, A. Suzuki, K. Hirahara, R. Shinnaksu, H. Hosokawa, A. Hasegawa, S. Motohashi, A. Iwama, and T. Nakayama
Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene
J. Exp. Med., May 12, 2008; 205(5): 1109 - 1120.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
K. Kalies, P. Konig, Y.-M. Zhang, M. Deierling, J. Barthelmann, C. Stamm, and J. Westermann
Nonoverlapping Expression of IL10, IL12p40, and IFN{gamma} mRNA in the Marginal Zone and T Cell Zone of the Spleen after Antigenic Stimulation
J. Immunol., April 15, 2008; 180(8): 5457 - 5465.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Scabeni, M. Lapilla, S. Musio, B. Gallo, E. Ciusani, L. Steinman, R. Mantegazza, and R. Pedotti
CD4+CD25+ Regulatory T Cells Specific for a Thymus-Expressed Antigen Prevent the Development of Anaphylaxis to Self
J. Immunol., April 1, 2008; 180(7): 4433 - 4440.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
C. Kurts
Th17 cells: a third subset of CD4+ T effector cells involved in organ-specific autoimmunity
Nephrol. Dial. Transplant., March 1, 2008; 23(3): 816 - 819.
[Full Text] [PDF]

Home page
 Toxicol SciHome page
J. Liu, M. Ballaney, U. Al-alem, C. Quan, X. Jin, F. Perera, L.-C. Chen, and R. L. Miller
Combined Inhaled Diesel Exhaust Particles and Allergen Exposure Alter Methylation of T Helper Genes and IgE Production In Vivo
Toxicol. Sci., March 1, 2008; 102(1): 76 - 81.
[Abstract] [Full Text] [PDF]

Home page
 J. Am. Soc. Nephrol.Home page
R. K. S. Phoon, A. R. Kitching, D. Odobasic, L. K. Jones, T. J. Semple, and S. R. Holdsworth
T-bet Deficiency Attenuates Renal Injury in Experimental Crescentic Glomerulonephritis
J. Am. Soc. Nephrol., March 1, 2008; 19(3): 477 - 485.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
K. S. Weber, M. J. Miller, and P. M. Allen
Th17 Cells Exhibit a Distinct Calcium Profile from Th1 and Th2 Cells and Have Th1-Like Motility and NF-AT Nuclear Localization
J. Immunol., February 1, 2008; 180(3): 1442 - 1450.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. Sun, C. J. Krawczyk, and E. J. Pearce
Suppression of Th2 Cell Development by Notch Ligands Delta1 and Delta4
J. Immunol., February 1, 2008; 180(3): 1655 - 1661.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
A. S. MacDonald and R. M. Maizels
Alarming dendritic cells for Th2 induction
J. Exp. Med., January 21, 2008; 205(1): 13 - 17.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. L. Graham
Ecological rules governing helminth microparasite coinfection
PNAS, January 15, 2008; 105(2): 566 - 570.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
G. Deniz, G. Erten, U. C. Kucuksezer, D. Kocacik, C. Karagiannidis, E. Aktas, C. A. Akdis, and M. Akdis
Regulatory NK Cells Suppress Antigen-Specific T Cell Responses
J. Immunol., January 15, 2008; 180(2): 850 - 857.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
A. Biswas, P. Banerjee, and T. Biswas
Priming of CD4+ T cells with porin of Shigella dysenteriae activates the cells toward type 1 polarization
Int. Immunol., January 1, 2008; 20(1): 81 - 88.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. H. Niess, F. Leithauser, G. Adler, and J. Reimann
Commensal Gut Flora Drives the Expansion of Proinflammatory CD4 T Cells in the Colonic Lamina Propria under Normal and Inflammatory Conditions
J. Immunol., January 1, 2008; 180(1): 559 - 568.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
J. S. H. Gaston
Cytokines in arthritis the 'big numbers' move centre stage
Rheumatology, January 1, 2008; 47(1): 8 - 12.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
D. A. Jabs, R. A. Prendergast, A. L. Campbell, B. Lee, E. K. Akpek, H. C. Gerard, A. P. Hudson, and J. A. Whittum-Hudson
Autoimmune Th2-Mediated Dacryoadenitis in MRL/MpJ Mice Becomes Th1-Mediated in IL-4 Deficient MRL/MpJ Mice
Invest. Ophthalmol. Vis. Sci., December 1, 2007; 48(12): 5624 - 5629.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
M. Moeller, M. H. Kershaw, R. Cameron, J. A. Westwood, J. A. Trapani, M. J. Smyth, and P. K. Darcy
Sustained Antigen-Specific Antitumor Recall Response Mediated by Gene-Modified CD4+ T Helper-1 and CD8+ T Cells
Cancer Res., December 1, 2007; 67(23): 11428 - 11437.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
D. Noguchi, D. Wakita, M. Tajima, S. Ashino, Y. Iwakura, Y. Zhang, K. Chamoto, H. Kitamura, and T. Nishimura
Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a Th17-independent manner
Int. Immunol., December 1, 2007; 19(12): 1431 - 1440.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
T. L Davis and J. L Pate
Bovine Luteal Cells Stimulate Proliferation of Major Histocompatibility Nonrestricted Gamma Delta T Cells
Biol Reprod, December 1, 2007; 77(6): 914 - 922.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
D. D. Sloan and K. R. Jerome
Herpes Simplex Virus Remodels T-Cell Receptor Signaling, Resulting in p38-Dependent Selective Synthesis of Interleukin-10
J. Virol., November 15, 2007; 81(22): 12504 - 12514.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
A. Koncz, M. Pasztoi, M. Mazan, F. Fazakas, E. Buzas, A. Falus, and G. Nagy
Nitric Oxide Mediates T Cell Cytokine Production and Signal Transduction in Histidine Decarboxylase Knockout Mice
J. Immunol., November 15, 2007; 179(10): 6613 - 6619.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
I. M. Irmler, M. Gajda, and R. Brauer
Exacerbation of Antigen-Induced Arthritis in IFN-{gamma}-Deficient Mice As a Result of Unrestricted IL-17 Response
J. Immunol., November 1, 2007; 179(9): 6228 - 6236.
[Abstract] [Full Text] [PDF]

Home page
 Evid Based Complement Alternat MedHome page
T. Matsumoto, M. Noguchi, O. Hayashi, K. Makino, and H. Yamada
Hochuekkito, a Kampo (traditional Japanese herbal) Medicine, Enhances Mucosal IgA Antibody Response in Mice Immunized with Antigen-entrapped Biodegradable Microparticles
Evid. Based Complement. Altern. Med., October 29, 2007; (2007) nem166v1.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
S. B. Su, R. S. Grajewski, D. Luger, R. K. Agarwal, P. B. Silver, J. Tang, J. Tuo, C.-C. Chan, and R. R. Caspi
Altered Chemokine Profile Associated with Exacerbated Autoimmune Pathology under Conditions of Genetic Interferon-{gamma} Deficiency
Invest. Ophthalmol. Vis. Sci., October 1, 2007; 48(10): 4616 - 4625.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
O. Stuve, T. N. Eagar, E. M. Frohman, and P. D. Cravens
DNA Plasmid Vaccination for Multiple Sclerosis
Arch Neurol, October 1, 2007; 64(10): 1385 - 1386.
[Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Joetham, K. Takeda, N. Miyahara, S. Matsubara, H. Ohnishi, T. Koya, A. Dakhama, and E. W. Gelfand
Activation of naturally occurring lung CD4+CD25+ regulatory T cells requires CD8 and MHC I interaction
PNAS, September 18, 2007; 104(38): 15057 - 15062.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
B. J. E. Raveney and D. J. Morgan
Dynamic Control of Self-Specific CD8+ T Cell Responses via a Combination of Signals Mediated by Dendritic Cells
J. Immunol., September 1, 2007; 179(5): 2870 - 2879.
[Abstract] [Full Text] [PDF]

Home page
 JEMHome page
F. Annunziato, L. Cosmi, V. Santarlasci, L. Maggi, F. Liotta, B. Mazzinghi, E. Parente, L. Fili, S. Ferri, F. Frosali, et al.
Phenotypic and functional features of human Th17 cells
J. Exp. Med., August 6, 2007; 204(8): 1849 - 1861.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
C.-H. Hsing, C.-C. Hsu, W.-Y. Chen, L.-Y. Chang, J.-C. Hwang, and M.-S. Chang
Expression of IL-19 correlates with Th2 cytokines in uraemic patients
Nephrol. Dial. Transplant., August 1, 2007; 22(8): 2230 - 2238.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. H. M. L. P. Navarathna, K. W. Nickerson, G. E. Duhamel, T. R. Jerrels, and T. M. Petro
Exogenous Farnesol Interferes with the Normal Progression of Cytokine Expression during Candidiasis in a Mouse Model
Infect. Immun., August 1, 2007; 75(8): 4006 - 4011.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
R. H. Straub
The Complex Role of Estrogens in Inflammation
Endocr. Rev., August 1, 2007; 28(5): 521 - 574.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
W. T. Khaled, E. K. C. Read, S. E. Nicholson, F. O. Baxter, A. J. Brennan, P. J. Came, N. Sprigg, A. N. J. McKenzie, and C. J. Watson
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development
Development, August 1, 2007; 134(15): 2739 - 2750.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Sandig, J. McDonald, J. Gilmour, M. Arno, T. H. Lee, and D. J. Cousins
Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone
PNAS, July 24, 2007; 104(30): 12440 - 12444.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
J. N. Kline
Eat Dirt: CpG DNA and Immunomodulation of Asthma
Proceedings of the ATS, July 1, 2007; 4(3): 283 - 288.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
Y. Inukai, A. Momobayashi, N. Sugawara, and Y. Aso
Changes in expression of T-helper (Th) 1- and Th2-associated chemokine receptors on peripheral blood lymphocytes and plasma concentrations of their ligands, interferon-inducible protein-10 and thymus and activation-regulated chemokine, after antithyroid drug administration in hyperthyroid patients with Graves' disease
Eur. J. Endocrinol., June 1, 2007; 156(6): 623 - 630.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
S. Podgaec, M.S. Abrao, J.A. Dias Jr, L.V. Rizzo, R.M. de Oliveira, and E.C. Baracat
Endometriosis: an inflammatory disease with a Th2 immune response component
Hum. Reprod., May 1, 2007; 22(5): 1373 - 1379.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Y.-K. Kim, S.-Y. Oh, S. G. Jeon, H.-W. Park, S.-Y. Lee, E.-Y. Chun, B. Bang, H.-S. Lee, M.-H. Oh, Y.-S. Kim, et al.
Airway Exposure Levels of Lipopolysaccharide Determine Type 1 versus Type 2 Experimental Asthma
J. Immunol., April 15, 2007; 178(8): 5375 - 5382.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
M. Baba, B. Yong Ma, M. Nonaka, Y. Matsuishi, M. Hirano, N. Nakamura, N. Kawasaki, N. Kawasaki, and T. Kawasaki
Glycosylation-dependent interaction of Jacalin with CD45 induces T lymphocyte activation and Th1/Th2 cytokine secretion
J. Leukoc. Biol., April 1, 2007; 81(4): 1002 - 1011.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Radhakrishnan, K. R. Wiehagen, V. Pulko, V. Van Keulen, W. A. Faubion, K. L. Knutson, and L. R. Pease
Induction of a Th1 Response from Th2-Polarized T Cells by Activated Dendritic Cells: Dependence on TCR:Peptide-MHC Interaction, ICAM-1, IL-12, and IFN-{gamma}
J. Immunol., March 15, 2007; 178(6): 3583 - 3592.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1986 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1986 by The American Association of Immunologists, Inc. All rights reserved.