| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Immunology, Vol 136, Issue 5 1752-1758, Copyright © 1986 by American Association of Immunologists
ARTICLES |
M Amiot, A Bernard, B Raynal, W Knapp, C Deschildre and L Boumsell
In humans, the presence of two non-HLA class 1-like molecules, whose expression, similar to murine Tla, is restricted to cortical thymocytes, has been shown with monoclonal antibodies defining the first cluster of differentiation (CD1). We report here with the use of 12 anti-CD1 antibodies and a combination of technical approaches, the characterization of a third CD1 molecule. We show that we can presently define seven different epitopes on the three CD1 molecules: four epitopes are restricted to the 49,000 dalton molecule, two epitopes to the 45,000 dalton molecule, and one epitope to the 43,000 dalton molecule. We show that the association of the newly identified 45,000 dalton heavy chain with human beta2-microglobulin is weak. In addition we show the presence of a fourth non-HLA class I molecular species on the surface of normal human thymus cells.
This article has been cited by other articles:
|
|
 |
|
  Q.-Y. Chen and N. Jackson Human CD1D Gene Has TATA Boxless Dual Promoters: An SP1-Binding Element Determines the Function of the Proximal Promoter J. Immunol., May 1, 2004; 172(9): 5512 - 5521. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. d. C. Salamone, A. K. Mendiguren, G. V. Salamone, and L. Fainboim Membrane trafficking of CD1c on activated T cells J. Leukoc. Biol., October 1, 2001; 70(4): 567 - 577. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. del C. Salamone, G. A. Rabinovich, A. K. Mendiguren, G. V. Salamone, and L. Fainboim Activation-induced expression of CD1d antigen on mature T cells J. Leukoc. Biol., February 1, 2001; 69(2): 207 - 214. [Abstract] [Full Text]
|
|
|
|
|
|
U. E. Schaible, K. Hagens, K. Fischer, H. L. Collins, and S. H. E. Kaufmann Intersection of Group I CD1 Molecules and Mycobacteria in Different Intracellular Compartments of Dendritic Cells J. Immunol., May 1, 2000; 164(9): 4843 - 4852. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Balk, S Burke, J. Polischuk, M. Frantz, L Yang, S Porcelli, S. Colgan, and R. Blumberg Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium Science, July 8, 1994; 265(5169): 259 - 262. [Abstract] [PDF]
|
|
|
|
|
|
S. Balk, E. Ebert, R. Blumenthal, F. McDermott, K. Wucherpfennig, S. Landau, and R. Blumberg Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes Science, September 20, 1991; 253(5026): 1411 - 1415. [Abstract] [PDF]
|
|
|
|
|
|
C Dargemont, D Dunon, M. Deugnier, M Denoyelle, J. Girault, F Lederer, K. Le, F Godeau, J. Thiery, and B. Imhof Thymotaxin, a chemotactic protein, is identical to beta 2-microglobulin Science, November 10, 1989; 246(4931): 803 - 806. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
