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The Journal of Immunology, Vol 134, Issue 6 3746-3750, Copyright © 1985 by American Association of Immunologists

ARTICLES

The specificity of the high endothelial venule in bronchus-associated lymphoid tissue (BALT)

GJ van der Brugge-Gamelkoorn and G Kraal

By using an in vitro binding assay, the specificity of T and B cell adherence on high endothelial venules (HEV) of bronchus-associated lymphoid tissue (BALT) was studied in the rat and the guinea pig. It was found that the adherence specificity of the BALT HEV is different from that found in Peyer's patches and more closely resembles the specificity of the HEV in mesenteric lymph nodes. The data are discussed in view of a common mucosal immune system.


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B. Xu, N. Wagner, L. N. Pham, V. Magno, Z. Shan, E. C. Butcher, and S. A. Michie
Lymphocyte Homing to Bronchus-associated Lymphoid Tissue (BALT) Is Mediated by L-selectin/PNAd, {alpha}4{beta}1 Integrin/VCAM-1, and LFA-1 Adhesion Pathways
J. Exp. Med., May 19, 2003; 197(10): 1255 - 1267.
[Abstract] [Full Text] [PDF]


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