The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mehta, K
Right arrow Articles by Davies, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mehta, K
Right arrow Articles by Davies, P.

The Journal of Immunology, Vol 134, Issue 4 2053-2056, Copyright © 1985 by American Association of Immunologists

COMMUNICATIONS

Interferon-gamma requires serum retinoids to promote the expression of tissue transglutaminase in cultured human blood monocytes

K Mehta, G Lopez-Berestein, WT Moore and PJ Davies

The culture of HPBM in serum-containing medium induced a large accumulation of the protein cross-linking enzyme, tissue TGase. Immune IFN enhanced the expression of tissue TGase in cultured monocytes. Enzyme-inducing activity, both in normal and IFN-treated cells, was completely blocked by depleting the serum of the lipid fraction. The readdition of retinol at a physiologic concentration (1 micron) to delipidized serum completely restored the enzyme-inducing activity in cultured monocytes. Thus, serum retinoids seem to play an important regulatory role in the expression of tissue TGase gene in differentiating human monocytes.


This article has been cited by other articles:


Home page
 Cancer Res.Home page
M. Satpathy, L. Cao, R. Pincheira, R. Emerson, R. Bigsby, H. Nakshatri, and D. Matei
Enhanced Peritoneal Ovarian Tumor Dissemination by Tissue Transglutaminase
Cancer Res., August 1, 2007; 67(15): 7194 - 7202.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
S. S. Akimov and A. M. Belkin
Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin
Blood, September 1, 2001; 98(5): 1567 - 1576.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1985 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1985 by The American Association of Immunologists, Inc. All rights reserved.