The JI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     
 

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by O'Hara, R. M.
Right arrow Articles by Duncan, W. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by O'Hara, R. M., Jr
Right arrow Articles by Duncan, W. R.

The Journal of Immunology, Vol 133, Issue 3 1163-1167, Copyright © 1984 by American Association of Immunologists

ARTICLES

Antigen-specific xenogeneic CTL activity in the Syrian hamster

RM O'Hara Jr and WR Duncan

Previous studies of the Syrian hamster have demonstrated a lack of cytotoxic T lymphocyte (CTL) activity in vaccinia virus-infected animals. Our laboratory has reexamined CTL activity in both the classical inbred strains, MHA, CB, and LSH, as well as the recently inbred strain MIT. Primary and secondary CTL specific for the immunizing antigen have been detected after in vitro culture in MIT but were not demonstrable in the classical strains. Only lymph node cells of the responding animal demonstrated this activity, spleen cells being phenotypically devoid of such a response. Identification of the cell responsible for cytolysis as a T cell was demonstrated by nylon wool nonadherence, specificity on Con A blasts, and the lack of surface immunoglobulin, as demonstrated by cell-sorter analysis.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Website Copyright © 1984 by The American Association of Immunologists, Inc. All rights reserved.
All Contents Copyright © 1984 by The American Association of Immunologists, Inc. All rights reserved.