The JI PBL Intereron Source
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     
 


This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Civin, C. I.
Right arrow Articles by Shaper, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Civin, C. I.
Right arrow Articles by Shaper, J. H.

The Journal of Immunology, Vol 133, Issue 1 157-165, Copyright © 1984 by American Association of Immunologists


ARTICLES

Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG- 1a cells

CI Civin, LC Strauss, C Brovall, MJ Fackler, JF Schwartz and JH Shaper

The anti-My-10 mouse monoclonal antibody was raised against the immature human myeloid cell line KG-1a and was selected for nonreactivity with mature human granulocytes. Anti-My-10 immunoprecipitated a KG-1a cell surface protein with an apparent Mr of approximately 115 kD. We describe the binding of this antibody to human hematopoietic cell types and show that My-10 is expressed specifically on immature normal human marrow cells, including hematopoietic progenitor cells. My-10 is also expressed by leukemic marrow cells from a subpopulation of patients. Thus, this antibody allows the identification and purification of hematopoietic progenitor cells from normal human marrow and the subclassification of leukemia.


This article has been cited by other articles:


Home page
J BiochemHome page
S. Hou, B. Li, L. Wang, W. Qian, D. Zhang, X. Hong, H. Wang, and Y. Guo
Humanization of an Anti-CD34 Monoclonal Antibody by Complementarity-determining Region Grafting Based on Computer-assisted Molecular Modelling
J. Biochem., July 1, 2008; 144(1): 115 - 120.
[Abstract] [Full Text] [PDF]


Home page
J. Histochem. Cytochem.Home page
L. M. Acevedo, I. Londono, M. Oubaha, L. Ghitescu, and M. Bendayan
Glomerular CD34 Expression in Short- and Long-term Diabetes
J. Histochem. Cytochem., June 1, 2008; 56(6): 605 - 614.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
E. Grinstein, Y. Du, S. Santourlidis, J. Christ, M. Uhrberg, and P. Wernet
Nucleolin Regulates Gene Expression in CD34-positive Hematopoietic Cells
J. Biol. Chem., April 27, 2007; 282(17): 12439 - 12449.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. Otto, X. Chen, W. J. Martin, W. Leung, J. Knowles, M. Holladay, J. Houston, R. Handgretinger, and R. C. Barfield
Selection of Stem Cells by Using Antibodies That Target Different CD34 Epitopes Yields Different Patterns of T-Cell Differentiation
Stem Cells, February 1, 2007; 25(2): 537 - 542.
[Abstract] [Full Text] [PDF]


Home page
ReproductionHome page
A. O Robb, N. L Mills, D. E Newby, and F. C Denison
Endothelial progenitor cells in pregnancy
Reproduction, January 1, 2007; 133(1): 1 - 9.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
U. Fiedler, S. Christian, S. Koidl, D. Kerjaschki, M. S. Emmett, D. O. Bates, G. Christofori, and H. G. Augustin
The Sialomucin CD34 Is a Marker of Lymphatic Endothelial Cells in Human Tumors
Am. J. Pathol., March 1, 2006; 168(3): 1045 - 1053.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
D. A. Hess, L. Wirthlin, T. P. Craft, P. E. Herrbrich, S. A. Hohm, R. Lahey, W. C. Eades, M. H. Creer, and J. A. Nolta
Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
Blood, March 1, 2006; 107(5): 2162 - 2169.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
F. Hermitte, P. Brunet de la Grange, F. Belloc, V. Praloran, and Z. Ivanovic
Very Low O2 Concentration (0.1%) Favors G0 Return of Dividing CD34+ Cells
Stem Cells, January 1, 2006; 24(1): 65 - 73.
[Abstract] [Full Text] [PDF]


Home page
J. Leukoc. Biol.Home page
V. Kindler
Postnatal stem cell survival: does the niche, a rare harbor where to resist the ebb tide of differentiation, also provide lineage-specific instructions?
J. Leukoc. Biol., October 1, 2005; 78(4): 836 - 844.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
K. Bartolovic, S. Balabanov, B. Berner, H.-J. Buhring, M. Komor, S. Becker, D. Hoelzer, L. Kanz, W.-K. Hofmann, and T. H. Brummendorf
Clonal Heterogeneity in Growth Kinetics of CD34+CD38- Human Cord Blood Cells In Vitro Is Correlated with Gene Expression Pattern and Telomere Length
Stem Cells, August 1, 2005; 23(7): 946 - 957.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
D. A. Hess, T. E. Meyerrose, L. Wirthlin, T. P. Craft, P. E. Herrbrich, M. H. Creer, and J. A. Nolta
Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
Blood, September 15, 2004; 104(6): 1648 - 1655.
[Abstract] [Full Text] [PDF]


Home page
IOVSHome page
E. M. Espana, T. Kawakita, C.-Y. Liu, and S. C. G. Tseng
CD-34 Expression by Cultured Human Keratocytes Is Downregulated during Myofibroblast Differentiation Induced by TGF-{beta}1
Invest. Ophthalmol. Vis. Sci., September 1, 2004; 45(9): 2985 - 2991.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
R. W. Georgantas III, V. Tanadve, M. Malehorn, S. Heimfeld, C. Chen, L. Carr, F. Martinez-Murillo, G. Riggins, J. Kowalski, and C. I. Civin
Microarray and Serial Analysis of Gene Expression Analyses Identify Known and Novel Transcripts Overexpressed in Hematopoietic Stem Cells
Cancer Res., July 1, 2004; 64(13): 4434 - 4441.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
D. C. Dooley, B. K. Oppenlander, and M. Xiao
Analysis of Primitive CD34- and CD34+ Hematopoietic Cells from Adults: Gain and Loss of CD34 Antigen by Undifferentiated Cells Are Closely Linked to Proliferative Status in Culture
Stem Cells, July 1, 2004; 22(4): 556 - 569.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. Murga, L. Yao, and G. Tosato
Derivation of Endothelial Cells from CD34- Umbilical Cord Blood
Stem Cells, May 1, 2004; 22(3): 385 - 395.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
N. Forraz, R. Pettengell, and C. P. McGuckin
Characterization of a Lineage-Negative Stem-Progenitor Cell Population Optimized for Ex Vivo Expansion and Enriched for LTC-IC
Stem Cells, January 1, 2004; 22(1): 100 - 108.
[Abstract] [Full Text] [PDF]


Home page
J. Histochem. Cytochem.Home page
T. Klein, Z. Ling, H. Heimberg, O. D. Madsen, R. S. Heller, and P. Serup
Nestin Is Expressed in Vascular Endothelial Cells in the Adult Human Pancreas
J. Histochem. Cytochem., June 1, 2003; 51(6): 697 - 706.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
Y. Guo, M. Lubbert, and M. Engelhardt
CD34- Hematopoietic Stem Cells: Current Concepts and Controversies
Stem Cells, January 1, 2003; 21(1): 15 - 20.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
H. S. Radomska, D. A. Gonzalez, Y. Okuno, H. Iwasaki, A. Nagy, K. Akashi, D. G. Tenen, and C. S. Huettner
Transgenic targeting with regulatory elements of the human CD34 gene
Blood, December 15, 2002; 100(13): 4410 - 4419.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
Y. Okuno, C. S. Huettner, H. S. Radomska, V. Petkova, H. Iwasaki, K. Akashi, and D. G. Tenen
Distal elements are critical for human CD34 expression in vivo
Blood, December 15, 2002; 100(13): 4420 - 4426.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Pathol.Home page
H Nakayama, H Enzan, E Miyazaki, and M Toi
{alpha} Smooth muscle actin positive stromal cells in gastric carcinoma
J. Clin. Pathol., October 1, 2002; 55(10): 741 - 744.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
S. J. Kuerbitz, J. Pahys, A. Wilson, N. Compitello, and T. A. Gray
Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia
Carcinogenesis, April 1, 2002; 23(4): 559 - 564.
[Abstract] [Full Text] [PDF]


Home page
Mol Hum ReprodHome page
J. M. Garcia-Pacheco, C. Oliver, M. Kimatrai, F. J. Blanco, and E. G. Olivares
Human decidual stromal cells express CD34 and STRO-1 and are related to bone marrow stromal precursors
Mol. Hum. Reprod., December 1, 2001; 7(12): 1151 - 1157.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Pathol.Home page
H Nakayama, H Enzan, E Miyazaki, N Kuroda, K Naruse, H Kiyoku, M Toi, and M Hiroi
CD34 positive stromal cells in gastric adenocarcinomas
J. Clin. Pathol., November 1, 2001; 54(11): 846 - 848.
[Abstract] [Full Text] [PDF]


Home page
Ann. N. Y. Acad. Sci.Home page
C. GIESERT, G. ALMEIDA-PORADA, A. SCHEFFOLD, L. KANZ, E. D. ZANJANI, and H.-J. BUHRING
The Monoclonal Antibody W7C5 Defines a Novel Surface Antigen on Hematopoietic Stem Cells
Ann. N.Y. Acad. Sci., June 1, 2001; 938(1): 175 - 183.
[Abstract] [Full Text] [PDF]


Home page
CMAJHome page
C. I. Chen and A. Keating
Beyond bone marrow: a new source of stem cells
Can. Med. Assoc. J., March 1, 2001; 164(5): 683 - 683.
[Full Text] [PDF]


Home page
BloodHome page
S. Matsuoka, Y. Ebihara, M.-j. Xu, T. Ishii, D. Sugiyama, H. Yoshino, T. Ueda, A. Manabe, R. Tanaka, Y. Ikeda, et al.
CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages
Blood, January 15, 2001; 97(2): 419 - 425.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
R. Sackstein and C. J. Dimitroff
A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity
Blood, October 15, 2000; 96(8): 2765 - 2774.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
J. Y. Lee, Z. Qu-Petersen, B. Cao, S. Kimura, R. Jankowski, J. Cummins, A. Usas, C. Gates, P. Robbins, A. Wernig, et al.
Clonal Isolation of Muscle-derived Cells Capable of Enhancing Muscle Regeneration and Bone Healing
J. Cell Biol., September 5, 2000; 150(5): 1085 - 1100.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. Sassetti, A. Van Zante, and S. D. Rosen
Identification of Endoglycan, a Member of the CD34/Podocalyxin Family of Sialomucins
J. Biol. Chem., March 17, 2000; 275(12): 9001 - 9010.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
C. Campagnoli, N. Fisk, T. Overton, P. Bennett, T. Watts, and I. Roberts
Circulating hematopoietic progenitor cells in first trimester fetal blood
Blood, March 15, 2000; 95(6): 1967 - 1972.
[Abstract] [Full Text] [PDF]


Home page
J. Gen. Virol.Home page
H. Isomura, M. Yoshida, H. Namba, N. Fujiwara, R. Ohuchi, F. Uno, M. Oda, Y. Seino, and M. Yamada
Suppressive effects of human herpesvirus-6 on thrombopoietin-inducible megakaryocytic colony formation in vitro
J. Gen. Virol., March 1, 2000; 81(3): 663 - 673.
[Abstract] [Full Text]


Home page
Stem CellsHome page
J. Baech and H. E. Johnsen
Technical Aspects and Clinical Impact of Hematopoietic Progenitor Subset Quantification
Stem Cells, March 1, 2000; 18(2): 76 - 86.
[Abstract] [Full Text]


Home page
BloodHome page
C. Cobaleda, N. Gutierrez-Cianca, J. Perez-Losada, T. Flores, R. Garcia-Sanz, M. Gonzalez, and I. Sanchez-Garcia
A primitive hematopoietic cell is the target for the leukemic transformation in human Philadelphia-positive acute lymphoblastic leukemia
Blood, February 1, 2000; 95(3): 1007 - 1013.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
A. W. Greenberg, W. G. Kerr, and D. A. Hammer
Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development
Blood, January 15, 2000; 95(2): 478 - 486.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
P Batard, M. Monier, N Fortunel, K Ducos, P Sansilvestri-Morel, T Phan, A Hatzfeld, and J. Hatzfeld
TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation
J. Cell Sci., January 2, 2000; 113(3): 383 - 390.
[Abstract] [PDF]


Home page
Stem CellsHome page
R. Huss
Isolation of Primary and Immortalized CD34- Hematopoietic and Mesenchymal Stem Cells from Various Sources
Stem Cells, January 1, 2000; 18(1): 1 - 9.
[Abstract] [Full Text]


Home page
Am. J. Pathol.Home page
Y. Natkunam, R. V. Rouse, S. Zhu, C. Fisher, and M. van de Rijn
Immunoblot Analysis of CD34 Expression in Histologically Diverse Neoplasms
Am. J. Pathol., January 1, 2000; 156(1): 21 - 27.
[Abstract] [Full Text] [PDF]


Home page
BMJHome page
P. A Fontes and A. W Thomson
Stem cell technology
BMJ, November 13, 1999; 319(7220): 1308 - 1308.
[Full Text]


Home page
BloodHome page
M. A. Goodell
CD34+ or CD34-: Does it Really Matter?
Blood, October 15, 1999; 94(8): 2545 - 2547.
[Full Text] [PDF]


Home page
BloodHome page
G. Theilmeier, T. Lenaerts, C. Remacle, D. Collen, J. Vermylen, and M. F. Hoylaerts
Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress
Blood, October 15, 1999; 94(8): 2725 - 2734.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
P. J. Roberts, E. Mollapour, M. J. Watts, and D. C. Linch
Primitive Myeloid Cells Express High Levels of Phospholipase A2 Activity in the Absence of Leukotriene Release: Selective Regulation by Stem Cell Factor Involving the MAP Kinase Pathway
Blood, August 15, 1999; 94(4): 1261 - 1272.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
R. W. Storms, A. P. Trujillo, J. B. Springer, L. Shah, O. M. Colvin, S. M. Ludeman, and C. Smith
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity
PNAS, August 3, 1999; 96(16): 9118 - 9123.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
J.-i. Tada, M. Omine, T. Suda, and N. Yamaguchi
A Common Signaling Pathway Via Syk and Lyn Tyrosine Kinases Generated From Capping of the Sialomucins CD34 and CD43 in Immature Hematopoietic Cells
Blood, June 1, 1999; 93(11): 3723 - 3735.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
J. J. Mattapallil, Z. Smit-McBride, and S. Dandekar
Gastrointestinal Epithelium Is an Early Extrathymic Site for Increased Prevalence of CD34+ Progenitor Cells in Contrast to the Thymus during Primary Simian Immunodeficiency Virus Infection
J. Virol., May 1, 1999; 73(5): 4518 - 4523.
[Abstract] [Full Text]


Home page
ScienceHome page
M. F. Pittenger, A. M. Mackay, S. C. Beck, R. K. Jaiswal, R. Douglas, J. D. Mosca, M. A. Moorman, D. W. Simonetti, S. Craig, and D. R. Marshak
Multilineage Potential of Adult Human Mesenchymal Stem Cells
Science, April 2, 1999; 284(5411): 143 - 147.
[Abstract] [Full Text]


Home page
J. Immunol.Home page
J. Plum, M. De Smedt, B. Verhasselt, F. Offner, T. Kerre, D. Vanhecke, G. Leclercq, and B. Vandekerckhove
In Vitro Intrathymic Differentiation Kinetics of Human Fetal Liver CD34+CD38- Progenitors Reveals a Phenotypically Defined Dendritic/T-NK Precursor Split
J. Immunol., January 1, 1999; 162(1): 60 - 68.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
A. Jiang, T.-H. T. Chu, F. Nocken, K. Cichutek, and R. Dornburg
Cell-Type-Specific Gene Transfer into Human Cells with Retroviral Vectors That Display Single-Chain Antibodies
J. Virol., December 1, 1998; 72(12): 10148 - 10156.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
K. Francis, R. Ramakrishna, W. Holloway, and B. O. Palsson
Two New Pseudopod Morphologies Displayed by the Human Hematopoietic KG1a Progenitor Cell Line and by Primary Human CD34+ Cells
Blood, November 15, 1998; 92(10): 3616 - 3623.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
T. M. Opie, L. E. Shields, and R. G. Andrews
Cell-Surface Antigen Expression in Early and Term Gestation Fetal Hematopoietic Progenitor Cells
Stem Cells, September 1, 1998; 16(5): 343 - 348.
[Abstract] [Full Text]


Home page
BloodHome page
R. E. Ryncarz and C. Anasetti
Expression of CD86 on Human Marrow CD34+ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells
Blood, May 15, 1998; 91(10): 3892 - 3900.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
H. Mayani and P. M. Lansdorp
Biology of Human Umbilical Cord Blood-Derived Hematopoietic Stem/Progenitor Cells
Stem Cells, May 1, 1998; 16(3): 153 - 165.
[Abstract] [Full Text]


Home page
BloodHome page
P. A. McSweeney, K. A. Rouleau, P. M. Wallace, B. Bruno, R. G. Andrews, L. Krizanac-Bengez, B. M. Sandmaier, R. Storb, E. Wayner, and R. A. Nash
Characterization of Monoclonal Antibodies That Recognize Canine CD34
Blood, March 15, 1998; 91(6): 1977 - 1986.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
M. C.-T. Hu and S. L. Chien
The Cytoplasmic Domain of Stem Cell Antigen CD34 Is Essential for Cytoadhesion Signaling But Not Sufficient for Proliferation Signaling
Blood, February 15, 1998; 91(4): 1152 - 1162.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
Y. Yamaguchi, L. I. Zon, S. J. Ackerman, M. Yamamoto, and T. Suda
Forced GATA-1 Expression in the Murine Myeloid Cell Line M1: Induction of c-Mpl Expression and Megakaryocytic/Erythroid Differentiation
Blood, January 15, 1998; 91(2): 450 - 457.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
T. D. Randall and I. L. Weissman
Characterization of a Population of Cells in the Bone Marrow that Phenotypically Mimics Hematopoietic Stem Cells: Resting Stem Cells or Mystery Population?
Stem Cells, January 1, 1998; 16(1): 38 - 48.
[Abstract] [Full Text]


Home page
BloodHome page
H. B. Wood, G. May, L. Healy, T. Enver, and G. M. Morriss-Kay
CD34 Expression Patterns During Early Mouse Development Are Related to Modes of Blood Vessel Formation and Reveal Additional Sites of Hematopoiesis
Blood, September 15, 1997; 90(6): 2300 - 2311.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
J. L. Hess, B. D. Yu, B. Li, R. Hanson, and S. J. Korsmeyer
Defects in Yolk Sac Hematopoiesis in Mll-Null Embryos
Blood, September 1, 1997; 90(5): 1799 - 1806.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. O. de Jong, Y. Westerman, G. Wagemaker, and A. W. Wognum
Coexpression of Kit and the Receptors for Erythropoietin, Interleukin 6 and GM-CSF on Hemopoietic Cells
Stem Cells, July 1, 1997; 15(4): 275 - 285.
[Abstract] [Full Text]


Home page
Stem CellsHome page
M. R. Koller, I. Manchel, and B. O. Palsson
Importance of Parenchymal:Stromal Cell Ratio for the Ex Vivo Reconstitution of Human Hematopoiesis
Stem Cells, July 1, 1997; 15(4): 305 - 313.
[Abstract] [Full Text]


Home page
BloodHome page
A.L. Petzer, C.J. Eaves, M.J. Barnett, and A.C. Eaves
Selective Expansion of Primitive Normal Hematopoietic Cells in Cytokine-Supplemented Cultures of Purified Cells From Patients With Chronic Myeloid Leukemia
Blood, July 1, 1997; 90(1): 64 - 69.
[Abstract] [Full Text] [PDF]